sigE

Overview

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
V166L	-	The V166L substitution falls within the SigE σ 2 /σ 4 linker, influencing transcription initiation.	Mycobacterium tuberculosis	Pyrazinamide	Reslit	Candidate

Papers1

Pyrazinamide Susceptibility Is Driven by Activation of the SigE-Dependent Cell Envelope Stress Response in Mycobacterium tuberculosis.

The V166L substitution falls within the SigE σ 2 /σ 4 linker, influencing transcription initiation.

Protein Change: V166L
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Pyrazinamide
Effect on Function: The V166L substitution falls within the SigE σ 2 /σ 4 linker, influencing transcription initiation.
Source Database: Reslit