smeB

Inner membrane multidrug exporter

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic efflux
Validation Method: CARD database analysis
Drug Classes: Tetracycline, Fluoroquinolone, Macrolide
Organisms: Pannonibacter phragmitetus 31801, Stenotrophomonas maltophilia
Papers: 1
Databases: Card DatabaseReslit

Papers1

Genomic insights of Pannonibacter phragmitetus strain 31801 isolated from a patient with a liver abscess.

PMID 28857514 · 2017

The study identified a β-lactam resistance gene, NPS β-lactamase, and several multidrug resistance efflux pump genes, including acrB, cmeB, macA, and macB, in Pannonibacter phragmitetus strain 31801, which contributes to its resistance to various antibiotics.

Gene Information

Gene Name: smeB
Allele: smeB
Encodes: Inner membrane multidrug exporter
Source Database: Reslit
Confers Resistance To: TetracyclineFluoroquinoloneMacrolide
Organisms Tested In: • Pannonibacter phragmitetus 31801
Validation Method: CARD database analysis
Sequence Accession: CP013068|CP013069

PMID N/A

Gene Information

Gene Name: smeB
Allele: smeB
Encodes: resistance-nodulation-cell division (RND) antibiotic efflux pump
Source Database: Card Database
Mechanism: antibiotic efflux
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AF173226.1
Protein Accession: AAD51345.1
Notes: ARO:3003052

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smeB

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