smeab

multidrug efflux pump

Validation StatusCandidate

Overview

Validation Method: antimicrobial susceptibility tests and restoration of resistance by plasmid introduction
Drug Classes: Erythromycin, Tetracycline, Chloramphenicol, Nalidixic acid, Rifampin, Neomycin, Kanamycin, Novobiocin, Vancomycin, Polymyxin b, Acriflavine
Organisms: Sinorhizobium meliloti
Papers: 1
Databases: Reslit

Papers1

Involvement of the smeAB multidrug efflux pump in resistance to plant antimicrobials and contribution to nodulation competitiveness in Sinorhizobium meliloti.

PMID 21398477 · 2011

The study identifies the SmeAB multidrug efflux pump as a major contributor to antimicrobial resistance and nodulation competitiveness in Sinorhizobium meliloti.

Gene Information

Gene Name: smeab
Allele: smeAB
Encodes: multidrug efflux pump
Source Database: Reslit
Confers Resistance To: ErythromycinTetracyclineChloramphenicolNalidixic acidRifampinNeomycinKanamycinNovobiocinVancomycinPolymyxin bAcriflavine
Organisms Tested In: • Sinorhizobium meliloti
Validation Method: antimicrobial susceptibility tests and restoration of resistance by plasmid introduction

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smeab

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