Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ATP-binding cassette (ABC) antibiotic efflux pump;major facilitator superfamily (MFS) antibiotic efflux pump;resistance-nodulation-cell division (RND) antibiotic efflux pump
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| R20H | - | single resistance variant, redox-sensitive transcriptional activator SoxR | Salmonella enterica, Escherichia coli | ciprofloxacinmultiple antibioticsampicillin+4 more | Card DatabaseReference Gene CatalogReslit | Confirmed |
| G121D | - | single resistance variant, redox-sensitive transcriptional activator SoxR | Escherichia coli, Salmonella enterica | ciprofloxacinfluoroquinolonesmultiple antibiotics+5 more | Card DatabaseReference Gene CatalogReslit | Confirmed |
| E16G | - | - | Salmonella enterica | ciprofloxacin | Reslit | Candidate |
| R20C | - | - | - | phenicolsciprofloxacin | Reslit | Candidate |
| R20L | - | - | Escherichia coli | ciprofloxacin | Reslit | Candidate |
| R123H | - | - | Escherichia coli | ciprofloxacin | Reslit | Candidate |
| T133S | - | - | E. coli | enrofloxacin | Reslit | Candidate |
| R51H | - | - | Escherichia coli | ciprofloxacin | Reslit | Candidate |
| R127P | - | - | Escherichia coli | ciprofloxacin | Reslit | Candidate |
| G121K | - | - | - | doxycycline | Reslit | Candidate |
| I120E | - | - | - | doxycyclinethiamphenicol | Reslit | Candidate |
| G121N | - | - | - | doxycyclinethiamphenicol | Reslit | Candidate |
| G121P | - | - | - | doxycyclinethiamphenicolazithromycin | Reslit | Candidate |
| R71S | - | single resistance variant | Escherichia coli | multiple antibiotics | Card Database | Established |
| R90G | - | single resistance variant | Escherichia coli | multiple antibiotics | Card Database | Established |
| S31A | - | single resistance variant | Escherichia coli | multiple antibiotics | Card Database | Established |
| T38S | - | multiple resistance variants | Escherichia coli | multiple antibiotics | Card Database | Established |
| G74R | - | multiple resistance variants | Escherichia coli | multiple antibiotics | Card Database | Established |
| L148fs | - | frameshift mutation | Escherichia coli | multiple antibiotics | Card Database | Established |
| S128del | - | redox-sensitive transcriptional activator SoxR | Escherichia coli | ampicillinphenicolsquinolones+2 more | Reference Gene Catalog | Established |
| - | - | Escherichia coli | minocyclinemeropenemaztreonam | Reslit | Candidate | |
| G39S | - | Acinetobacter baumannii | phenicolstetracyclinetigecycline+3 more | Reslit | Candidate | |
| V20L | - | Salmonella Typhimurium | ciprofloxacin | Reslit | Candidate |
No comments yet. Be the first to comment!