sul1

sulfonamide resistance protein

Validation StatusSupported

Overview

Validation Method: cloning and susceptibility testing
Drug Classes: sulfamethoxazole, sulfonamides, sulfonamide
Organisms: Klebsiella pneumoniae, Escherichia coli, Salmonella enterica serovar Typhimurium, Pseudomonas aeruginosa
Geographic Location: Australia, Czech Republic
Papers: 4
Databases: Reslit

Papers4

In34, a complex In5 family class 1 integron containing orf513 and dfrA10.

PMID 12499211 · 2003

The study identifies and characterizes the class 1 integron In34, which contains multiple antibiotic resistance genes including aadB, dfrA10, aphA1, catA1, blaTEM, and sul1. These genes confer resistance to various antibiotics such as gentamicin, kanamycin, tobramycin, trimethoprim, chloramphenicol, ampicillin, and sulfamethoxazole.

Gene Information

Gene Name: sul1
Allele: Sul1
Encodes: sulfonamide resistance protein
Source Database: Reslit
Confers Resistance To: sulfamethoxazole
Organisms Tested In: • Klebsiella pneumoniae
• Escherichia coli
Geographic Location: Australia
Validation Method: cloning and susceptibility testing
Sequence Accession: AY123253

Evolution of antibiotic resistance in Salmonella enterica serovar typhimurium strains isolated in the Czech Republic between 1984 and 2002.

PMID 12760885 · 2003

The study identifies the aadA21 gene, a novel variant of the aadA gene, and other resistance genes such as blaPSE-1, floR, sul1, and tetG in Salmonella enterica serovar Typhimurium strains from the Czech Republic between 1984 and 2002.

Gene Information

Gene Name: sul1
Allele: Sul1
Encodes: sulfonamide resistance protein
Source Database: Reslit
Confers Resistance To: sulfonamides
Organisms Tested In: • Salmonella enterica serovar Typhimurium
Geographic Location: Czech Republic
Validation Method: PCR and DNA sequencing
Sequence Accession: AY171244

Mechanisms of resistance in multiple-antibiotic-resistant Escherichia coli strains of human, animal, and food origins.

PMID 15388464 · 2004

Gene Information

Gene Name: sul1
Allele: Sul1
Encodes: sulfonamide resistance protein
Source Database: Reslit
Confers Resistance To: sulfamethoxazole
Organisms Tested In: • Escherichia coli
Validation Method: PCR and sequencing

The IncP-6 plasmid Rms149 consists of a small mobilizable backbone with multiple large insertions.

PMID 15995187 · 2005

The study characterizes the IncP-6 plasmid Rms149, identifying several AMR genes including aac(3)-I, aadA5, intI1, qacEΔ1, and sul1, which confer resistance to gentamicin, streptomycin, spectinomycin, quaternary ammonium compounds, and sulfonamide, respectively.

Gene Information

Gene Name: sul1
Allele: Sul1
Encodes: sulfonamide resistance
Source Database: Reslit
Confers Resistance To: sulfonamide
Organisms Tested In: • Pseudomonas aeruginosa
• Escherichia coli
Validation Method: cloning and functional analysis
Sequence Accession: AJ877225

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sul1

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