tet(32)

tetracycline resistance protein

Validation StatusCandidate

Overview

Validation Method: PCR amplification and sequencing, MIC testing
Drug Classes: tetracycline
Organisms: Clostridium-related human colonic anaerobe K10, Butyrivibrio fibrisolvens 2221 R, Clostridium -like fecal strain K-10, Megasphaera elsdenii
Papers: 2
Databases: Reslit

Papers2

Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens.

PMID 11600392 · 2001

A novel tetracycline resistance gene, tet(32), was identified in the Clostridium-related human colonic anaerobe K10 and transmitted in vitro to the rumen anaerobe Butyrivibrio fibrisolvens. The gene confers high-level tetracycline resistance and is widely distributed in the ovine rumen and porcine feces.

Gene Information

Gene Name: tet(32)
Allele: Tet(32)
Encodes: tetracycline resistance protein
Source Database: Reslit
Confers Resistance To: tetracycline
Organisms Tested In: • Clostridium-related human colonic anaerobe K10
• Butyrivibrio fibrisolvens 2221 R
Validation Method: PCR amplification and sequencing, MIC testing
Sequence Accession: AJ295238

Hybrid tet genes and tet gene nomenclature: request for opinion.

PMID 15728946 · 2005

The paper discusses the discovery of hybrid tetracycline resistance genes, including tet(32), which is a recombinant of tet(O) and an unknown tet gene, and proposes a new nomenclature system for such hybrid genes.

Gene Information

Gene Name: tet(32)
Allele: Tet(32)
Encodes: ribosomal protection-type protein
Source Database: Reslit
Confers Resistance To: tetracycline
Organisms Tested In: • Clostridium -like fecal strain K-10
• Megasphaera elsdenii
Validation Method: sequence analysis and functional characterization
Sequence Accession: AY485122|AY196921|AY196920|AJ295238

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tet(32)

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