Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
open reading frame (ORF) 154 amino acids long
Overview
New Mg2+-dependent oxytetracycline resistance determinant tet 34 in Vibrio isolates from marine fish intestinal contents.
A new Mg2+-dependent oxytetracycline resistance determinant, Tet34, was identified in Vibrio sp. no. 6. The gene encodes an ORF homologous to xanthine-guanine phosphoribosyltransferases (XPRTs) and confers resistance to oxytetracycline in E. coli.
New Mg2+-dependent oxytetracycline resistance determinant tet 34 in Vibrio isolates from marine fish intestinal contents.
Environmental macrolide-lincosamide-streptogramin and tetracycline resistant bacteria.
The paper discusses the characterization of environmental macrolide-lincosamide-streptogramin (MLS) and tetracycline resistance genes, highlighting the diversity and distribution of these genes in environmental bacteria. It identifies several MLS resistance genes such as erm(H), erm(I), erm(N), and others, as well as tetracycline resistance genes like tetA(P), tet(V), and tet(X).
pirAB(vp)-Bearing Vibrio parahaemolyticus and Vibrio campbellii Pathogens Isolated from the Same AHPND-Affected Pond Possess Highly Similar Pathogenic Plasmids.
The study identifies antibiotic resistance genes in Vibrio parahaemolyticus and Vibrio campbellii strains isolated from an AHPND-affected pond, highlighting the presence of tetracycline, sulfonamide, streptomycin, and florfenicol resistance mechanisms.
The complete genome sequence of Vibrio aestuarianus W-40 reveals virulence factor genes.
The study identified bacA and tet34 genes in Vibrio aestuarianus strain W-40, which confer resistance to bacitracin and tetracycline, respectively.
Current Status of the Use of Antibiotics and the Antimicrobial Resistance in the Chilean Salmon Farms.
The study identifies several AMR genes, including floR, tet(A), tet(B), tet(H), tet(l), tet(34), tet(35), aac(6')-Ib-cr, and intI1, associated with resistance to florfenicol, oxytetracycline, quinolones, and kanamycin in Chilean salmon farming environments.
Extended antibiotic treatment in salmon farms select multiresistant gut bacteria with a high prevalence of antibiotic resistance genes.
The study identifies several AMR genes, including floR, fexA, and various tetracycline resistance genes (tetA, tetB, tetE, tetH, tetL, tetM, tet34, tet35), associated with resistance to florfenicol and oxytetracycline in gut bacteria from salmon farms. These genes were found in multiple bacterial species, highlighting the widespread nature of AMR in aquatic environments.
Phenotypic and Genotypic Antimicrobial Resistance Traits of Vibrio cholerae Non-O1/Non-O139 Isolated From a Large Austrian Lake Frequently Associated With Cases of Human Infection.
The study identified beta-lactam resistance genes bla CARB–7 and bla CARB–9, the phenicol resistance gene catB9, and the tetracycline resistance gene tet (34) in Vibrio cholerae non-O1/non-O139 isolates from a large Austrian lake. These genes were associated with resistance to ampicillin, chloramphenicol, and tetracycline, respectively.
Impact of short-term storage on the quantity of extended-spectrum beta-lactamase-producing Escherichia coli in broiler litter under practical conditions.
The study identified bla SHV-12, bla CTX-M-1, and bla TEM-1 as the primary beta-lactamase genes in ESBL-producing E. coli isolates from broiler litter. Additional resistance mechanisms included qnrS1, mdfA, and Tet 34.
Comparative analysis of multidrug resistance plasmids and genetic background of CTX-M-producing Escherichia coli recovered from captive wild animals.
The study identifies multiple AMR genes and mutations in MDR E. coli strains from captive wild animals, highlighting the presence of CTX-M-8 and CTX-M-65 beta-lactamases, along with various other resistance mechanisms such as aminoglycoside, tetracycline, and fluoroquinolone resistance genes, as well as mutations in quinolone resistance-determining regions.
Vibrios from the Norwegian marine environment: Characterization of associated antibiotic resistance and virulence genes.
The study identified various antibiotic resistance genes in Vibrio isolates from the Norwegian marine environment, including beta-lactamases (blaCARB, blaampC, varG), tetracycline resistance genes (tet34, tet35), a multidrug efflux pump (adeF), a quinolone resistance gene (qnr), and a chloramphenicol resistance gene (catB-related).
Identification of Antimicrobial Resistance Determinants in Aeromonas veronii Strain MS-17-88 Recovered From Channel Catfish (Ictalurus punctatus).
The study identified multiple antimicrobial resistance genes in Aeromonas veronii strain MS-17-88, including beta-lactamase genes (imiS, ampS), phenicol resistance genes (floR, catB2, catB7, vat(F)), colistin resistance genes (mcr-3, mcr-7.1), tetracycline resistance genes (tet(34), tet(35), tet(E)), and a trimethoprim resistance gene (dfrA3).
Complete genome analysis of a virulent Vibrio scophthalmi strain VSc190401 isolated from diseased marine fish half-smooth tongue sole, Cynoglossus semilaevis.
The study identified several AMR genes in Vibrio scophthalmi strain VSc190401, including those conferring resistance to aminoglycosides, fluoroquinolones, tetracyclines, and polymyxins. Some of these genes were validated experimentally.
Genome-based characterization of two Colombian clinical Providencia rettgeri isolates co-harboring NDM-1, VIM-2, and other β-lactamases.
Two Colombian clinical Providencia rettgeri isolates co-harboring NDM-1, VIM-2, and other β-lactamases were characterized. The isolates exhibited resistance to multiple antibiotics, including carbapenems, cephalosporins, and aminoglycosides.
Genome- and Proteome-Wide Analysis of Lysine Acetylation in Vibrio vulnificus Vv180806 Reveals Its Regulatory Roles in Virulence and Antibiotic Resistance.
The study identifies varG, tet(34), and tet(35) as antibiotic resistance genes in Vibrio vulnificus Vv180806, with varG showing beta-lactamase activity against penicillins, carbapenems, and cephalosporins, contributing to cefoxitin resistance.
Antibiotic-Resistant Enterobacteriaceae in Wastewater of Abattoirs.
The study identified multidrug-resistant Enterobacteriaceae in wastewater from slaughterhouses, including ESBL-producing E. coli and K. pneumoniae, as well as colistin-resistant strains carrying mcr-1.1, bla CTX-M-15, and tet(34).
Effects of Ursolic Acid on Intestinal Health and Gut Bacteria Antibiotic Resistance in Mice.
Ursolic acid reduced the expression of tetracycline resistance genes in the gut microbiota of antibiotic-exposed mice.
HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities.
The study identified various AMR genes, including aadA1, aadA2, blaCFE-1, cmlA1, dfrA12, mdf(A), sul3, tet(34), and lnu(A), in pig fecal microbiomes. Notably, the lnu(A) gene was exclusively found in conventional farms and associated with Lactobacillus species.
Evaluating the potential of third generation metagenomic sequencing for the detection of BRD pathogens and genetic determinants of antimicrobial resistance in chronically ill feedlot cattle.
The study identified various antimicrobial resistance genes (ARGs) in metagenomic sequencing data from chronically ill feedlot cattle, including genes conferring resistance to beta-lactams, aminoglycosides, macrolides, phenicols, tetracyclines, and trimethoprim. Notably, tetH was the most frequently detected resistance gene, and several ARGs were found to be associated with integrative and conjugative elements (ICEs).
Emergence, Dissemination and Antimicrobial Resistance of the Main Poultry-Associated Salmonella Serovars in Brazil.
The study characterizes antimicrobial resistance (AMR) genes and mutations in various Salmonella serovars associated with poultry in Brazil, emphasizing the emergence of multidrug-resistant (MDR) strains. Key findings include the identification of AMR genes such as blaCTX-M-2, blaTEM-1B, aac(3)-lla, aac(3)-lld, aadA1, aadA2, aph(6)-ld, dfrA1, floR, mrc-1, strA, strB, sul1, sul2, tet(A), tet(B), and others, which confer resistance to multiple antibiotics.
Taxonomic Assignment-Based Genome Reconstruction from Apical Periodontal Metagenomes to Identify Antibiotic Resistance and Virulence Factors.
The study identified several antibiotic resistance genes (ARGs) in metagenomic assemblies from apical periodontal infections, highlighting the presence of multidrug resistance mechanisms in Enterobacter and Pseudomonas species.
Molluscs-A ticking microbial bomb.
The paper discusses the presence of antibiotic resistance genes (ARGs) in bivalve molluscs, highlighting the spread of resistance to various antibiotics such as colistin, beta-lactams, fluoroquinolones, and tetracyclines. It emphasizes the role of bivalve aquacultures in the dissemination of ARGs and the potential risks to human health through the food chain.
Molluscs-A ticking microbial bomb.
The paper discusses the presence of antibiotic resistance genes (ARGs) in bivalve molluscs, highlighting the spread of resistance to various antibiotics such as colistin, beta-lactams, fluoroquinolones, and tetracyclines. It emphasizes the role of bivalve aquacultures in the dissemination of ARGs and the potential risks to human health through the food chain.
Incidence, genetic diversity, and antimicrobial resistance profiles of Vibrio parahaemolyticus in seafood in Bangkok and eastern Thailand.
The study identified several antimicrobial resistance genes in Vibrio parahaemolyticus isolates from seafood in Bangkok and eastern Thailand, including blaCARB, tet(34), tet(35), qnrC, dfrA6, and blaCTX-M-55, which confer resistance to various antibiotics such as ampicillin, amoxicillin, piperacillin, tetracycline, doxycycline, ciprofloxacin, and trimethoprim.
Genetic Diversity and Antimicrobial Resistance of Extraintestinal E. coli Populations Pre- and Post-Antimicrobial Therapy on Broilers Affected by Colisepticemia.
The study identified several AMR genes and mutations in extraintestinal E. coli populations from broilers treated with enrofloxacin. Key findings include the presence of qnrB19 and qnrS1 genes, which confer fluoroquinolone resistance, and mutations in gyrA, parC, and parE genes associated with fluoroquinolone resistance. Additionally, multiple other AMR genes were detected, indicating multidrug resistance.
Whole Genome Sequencing and Pan-Genomic Analysis of Multidrug-Resistant Vibrio cholerae VC01 Isolated from a Clinical Sample.
The study identified multiple AMR genes in the multidrug-resistant V. cholerae VC01 strain, including catB9, floR, tet(34), sul2, and dfrA1, which confer resistance to chloramphenicol, florfenicol, oxytetracycline, sulfonamide, and trimethoprim, respectively.
The Resistance and Virulence Characteristics of Salmonella Enteritidis Strain Isolated from Patients with Food Poisoning Based on the Whole-Genome Sequencing and Quantitative Proteomic Analysis.
The study identified multiple antimicrobial resistance genes in the multidrug-resistant Salmonella Enteritidis strain 27A, including beta-lactamase blaTEM-194, aminoglycoside resistance genes aac(6)-Ib, aac(6)-If, aph(3”)-Ib, and aph(6)-Id, tetracycline resistance genes tetA, tetR, and tet34, and efflux pump genes acrA, acrB, tolC, oprM, mexE, mexF, macB, mdtG, mdtH, mdtL, mdtM, mdtK, rosA, emrA, emrR, ykkc, and vanRA.
Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome.
The study found that doxy-PEP use over 6 months significantly increased the proportion and expression of tetracycline resistance genes in the gut microbiome, with no significant changes in other antibiotic resistance gene classes.
Antimicrobial resistance, virulence factors and phylogenetic profiles of Vibrio parahaemolyticus in the eastern coast of Shenzhen.
The study identified several antimicrobial resistance genes in Vibrio parahaemolyticus isolates from Shenzhen, including blaCARB, tet(34), tet(35), qnrVC6, sul2, aph(6)-Id, floR, cat, and blaCTX-M-14. These genes conferred resistance to various antibiotics such as ampicillin, tetracycline, fluoroquinolones, sulfonamides, aminoglycosides, chloramphenicol, and beta-lactams.
Genomic Insights of Antibiotic-Resistant Escherichia coli Isolated from Intensive Pig Farming in South Africa Using 'Farm-to-Fork' Approach.
The study identified multiple antibiotic resistance genes and mutations in E. coli isolates from intensive pig farming in South Africa, highlighting the spread of resistance across the pork production continuum.
Genome analysis of Actinobacillus pleuropneumoniae strain APPFJLYC01 reveals multidrug resistance and high virulence potential.
The study identified 10 antibiotic resistance genes in the Actinobacillus pleuropneumoniae strain APPFJLYC01, including genes conferring resistance to multiple antibiotic classes such as β-lactams, tetracyclines, aminoglycosides, and macrolides.
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