Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline resistance determinant
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Tet(44) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 16 | Tetracycline, Doxycycline +4 |
| Switzerland, Europe, global|Europe|Belgium, South Korea, Europe|Taiwan|USA, China, Asia|North America |
| 2010, 2011, 2016, 2017, 2021, 2023, 2024, 2025, 2026 |
| FN594949 |
| CBH51823.1 |
| tet-44 | Reslit | 1 | Tetracycline | Clostridioides difficile | Australia|Europe|Asia|North America|New Zealand | 2021 | NC_017174 | - |
| TET44 | Reslit | 2 | Tetracycline | Bacteroidetes +4 | Alberta, Canada | 2019, 2024 | - | - |
| tet44 | Reslit | 5 | Tetracycline | Bacteroides thetaiotaomicron +3 | Asia|Europe|North America|Australia/New Zealand, China, Canada, China|Xinjiang | 2020, 2021, 2023, 2025 | PRJNA504846|PRJNA515074 | - |
| tet(44) | Card DatabaseResFinder Database | 2 | MINOCYCLINE, TETRACYCLINE +1 | Clostridium perfringens C str. JGS1495, Campylobacter fetus subsp. fetus +1 | - | 2010 | ABDU01000081, FN594949 | CBH51823.1 |
Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus.
The study identifies two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. These genes confer resistance to tetracycline, doxycycline, minocycline, and streptomycin.
Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus.
Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus.
Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus.
Environmental macrolide-lincosamide-streptogramin and tetracycline resistant bacteria.
The paper discusses the characterization of environmental macrolide-lincosamide-streptogramin (MLS) and tetracycline resistance genes, highlighting the diversity and distribution of these genes in environmental bacteria. It identifies several MLS resistance genes such as erm(H), erm(I), erm(N), and others, as well as tetracycline resistance genes like tetA(P), tet(V), and tet(X).
Clinical and epidemiological analysis of Campylobacter fetus subsp. fetus infections in humans and comparative genetic analysis with strains isolated from cattle.
The study identified tetracycline resistance gene tet(44) and streptomycin resistance gene ant(6)-Ib in Campylobacter fetus subsp. fetus isolates, along with a genomic island containing a type IV secretion system (T4SS) associated with antibiotic resistance.
Bacteria from Animals as a Pool of Antimicrobial Resistance Genes.
The paper discusses the role of bacteria from animals as a reservoir of antimicrobial resistance genes, highlighting the presence of various AMR genes such as erm(B), tet(M), cfr, and others in different bacterial species, emphasizing their contribution to the spread of resistance.
Global Population Structure and Evolution of Clostridioides difficile ST11 and ST258 Lineages
The study identifies tetracycline resistance genes tetM and tet-44, along with the erythromycin resistance gene ermB, in C. difficile ST11 and ST258 lineages, highlighting their role in antimicrobial resistance.
Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent.
The study identified several tetracycline, macrolide, aminoglycoside, beta-lactam, sulfonamide, mercury, and biocide resistance genes in beef feedlots, catch basin water, soil, and urban sewage influent. Tetracycline resistance was predominant in beef production systems, while urban sewage influent showed a diverse resistome with resistance to multiple antimicrobial classes.
Metatranscriptomics Reveals Antibiotic-Induced Resistance Gene Expression in the Murine Gut Microbiota.
The study identifies specific AMR genes, including beta-lactamase genes (cepA, bl2e_cepA) and tetracycline resistance genes (tet32, tet44, tetW), that are upregulated in response to amoxicillin and doxycycline treatments in the murine gut microbiota.
The distribution of antibiotic resistance genes in chicken gut microbiota commensals.
The study identified various tetracycline resistance genes including tet(W), tet(Q), tet(32), tet(O), tet(44), tetA(P), and tetB(P) in chicken gut microbiota commensals, highlighting their distribution across different bacterial families.
Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection.
Nine Clostridioides difficile strains isolated from Korean patients were analyzed, revealing diverse antibiotic resistance genes including those conferring resistance to erythromycin, clindamycin, glycopeptides, fluoroquinolones, aminoglycosides, and tetracyclines.
A species-wide genetic atlas of antimicrobial resistance in Clostridioides difficile.
This study identifies multiple AMR genes and mutations in Clostridioides difficile, including ermB, tetM, mefH, and various mutations in gyrA, gyrB, rpoB, pbp1, and pbp3. These findings highlight the widespread nature of AMR in C. difficile and its potential role in the spread of the bacterium.
Antimicrobial resistance in Campylobacter fetus: emergence and genomic evolution.
The study identified several AMR genes and mutations in Campylobacter fetus, including ant(6)-Ib, aph(3')-III, tet(O), tet(44), and cat, which confer resistance to various antibiotics. Mutations in the gyrA gene were also found to contribute to fluoroquinolone resistance.
Molecular characteristics and phylogenetic analysis of Clostridium perfringens from different regions in China, from 2013 to 2021.
The study identified various AMR genes in Clostridium perfringens isolates from China, including mprF, tetA(P), tetB(P), ErmQ, LnuP, AAC(6′)-Ie-APH(2″)-Ia, ANT(6)-Ib, tet44, and ErmB, which confer resistance to antibiotics such as penicillin, tetracycline, clindamycin, and aminoglycosides.
Pathogenicity and Antibiotic Resistance Diversity in Clostridium perfringens Isolates from Poultry Affected by Necrotic Enteritis in Canada.
The study identified several antimicrobial resistance genes in Clostridium perfringens isolates from poultry with necrotic enteritis, including tetA, tetB, tet44, InuP, erm(T), and ant(6)-Ib. The erm(T) gene was reported for the first time in C. perfringens and conferred resistance to erythromycin.
Effects of Neolamarckia cadamba leaves extract on microbial community and antibiotic resistance genes in cecal contents and feces of broilers challenged with lipopolysaccharides.
The study found that Neolamarckia cadamba leaves extract (NCLE) reduced the abundance of antibiotic resistance genes (ARGs) in cecal contents of lipopolysaccharide (LPS)-induced broilers by maintaining microbial balance.
Metagenomics reveals the temporal dynamics of the rumen resistome and microbiome in goat kids.
The study identified numerous antibiotic resistance genes (ARGs) in the rumen of goat kids, highlighting the dynamic nature of the resistome influenced by age and diet. Key ARGs included RPOB, GYRA, GYRBA, ROB, MDTF, ACRF, ACRB, MGTA, MLS23S, TUFAB, TET44, TET32, APH2-DPRIME, SAT, BRO, TETQ, ERMF, NIMJ, ACI, MEFA, RRSC, RRSH, CAP16S, TETX, LNUC, TETW, TETO, and TET40, which were associated with resistance to various antibiotics such as drugs, MLS, tetracyclines, and others.
Virulence and resistance gene analysis of Rothia nasimurium by whole gene sequencing.
The study identified multiple AMR genes in Rothia nasimurium Y1, including vanA, vanC, vanB, vanE, vanD, vanG, vanF, vanM, vanL, vanO, vanN, mtrA, vanRA, arlR, vanRI, vanRB, vanRC, vanRD, vanRF, vanRG, CpxR, kdpE, vanRM, vanRN, baeR, adeR, vanRL, smeR, gyrA, gyrB, parC, Mfd, mfd, PBP2, PBP2x, EF-Tu, dfrE, pncA, tetB(P), tetQ, tet44, tetT, tetW, tetS, tetM, tetO, otr(A), tet36, tet32, clbC, clbB, clbA, cipA, cfrA, cfrC, sul3, ParY, murA, cls, and ileS, which confer resistance to various antibiotics such as glycopeptides, beta-lactams, fluoroquinolones, tetracyclines, sulfonamides, aminoglycosides, lincosamides, phenicols, macrolides, and others.
Genomic insights into the diversity, antimicrobial resistance and zoonotic potential of Campylobacter fetus across diverse hosts and geographies.
The study identified five AMR genes in Campylobacter fetus, including tet(O), tet(44), ant(6)-Ib, aph(3′)-III, and lnu(C), which confer resistance to tetracyclines, streptomycin, amikacin, and lincomycin. These genes were detected in human and animal isolates from various geographic regions.
Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.
The study identified several tetracycline, aminoglycoside, and MLS resistance genes in the fecal microbiome of gilts, with no significant increases in ARG abundance following exposure to semen extenders containing antibiotics.
Elucidation of population-based bacterial adaptation to antimicrobial treatment by single-cell sequencing analysis of the gut microbiome of a hospital patient.
The study identified 29 ARG subtypes across eight types in 13 known, five unknown, and 18 unclassified species, highlighting the complex and dynamic nature of antimicrobial resistance in the gut microbiome. Notably, the cfr(C) gene was detected in 11 bacterial species following antimicrobial treatment, with mutation patterns characterized in several species.
Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus.
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