Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline resistance protein
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| tet(45) | Card DatabaseResFinder Database | 2 | TETRACYCLINE, DOXYCYCLINE | Bhargavaea cecembensis | - | 2013 | JF837331 | AEM62948.1 |
| Tet(45) |
Card DatabaseReference Gene CatalogReslit |
| 13 |
| Tetracycline, Doxycycline +3 |
| Bacillus cereus +20 |
| China|Europe, Germany, Thailand, Europe|United States|Asia, Canada|United Kingdom|Alberta, Bangladesh, Saudi Arabia, South Africa|NWC|NWG, Spain|Portugal|Germany|UK|Switzerland|Thailand|Italy |
| 2016, 2019, 2021, 2022, 2023, 2024 |
| KX091844|KX091845|CP014284.1|CP014528.1|KT780704|CP012600.1 |
| ADE08372.2 |
| tet45 | Reslit | 2 | Tetracycline | Bacillus cereus group +1 | Europe, France | 2022, 2025 | PRJEB88997|PRJNA762634 | - |
Identification of Tet45, a tetracycline efflux pump, from a poultry-litter-exposed soil isolate and persistence of tet(45) in the soil.
Probiotic Bacillus cereus Strains, a Potential Risk for Public Health in China.
The study identified the tetracycline resistance gene tet(45) in Bacillus cereus strain 9i, which was transferable to Staphylococcus aureus and Bacillus subtilis via electro-transformation.
Antibiotics resistance and toxin profiles of Bacillus cereus-group isolates from fresh vegetables from German retail markets.
The study identified several AMR genes in Bacillus cereus-group isolates from fresh vegetables, including fosB, ykkC, lsaB, and tet(45). These genes were found to confer resistance to various antibiotics such as fosfomycin, tetracycline, and erythromycin.
Evaluation of Tetracycline Resistance and Determination of the Tentative Microbiological Cutoff Values in Lactic Acid Bacterial Species.
The study identified five tetracycline resistance genes (tet(M), tet(W/N/W), tet(L), tet(S), and tet(45)) in lactic acid bacteria (LAB) and determined species-specific microbiological cutoff values for tetracycline resistance.
Antimicrobial Susceptibility Profile and Whole-Genome Analysis of a Strong Biofilm-Forming Bacillus Sp. B87 Strain Isolated from Food.
Bacillus sp. B87 was found to be resistant to β-lactam antimicrobial agents and tetracycline, carrying the BcII and tet(45) genes respectively.
Comparative Analysis of Bacillus cereus Group Isolates' Resistance Using Disk Diffusion and Broth Microdilution and the Correlation between Antimicrobial Resistance Phenotypes and Genotypes.
The study identified several antimicrobial resistance genes in Bacillus cereus group isolates, including beta-lactamase-encoding genes (bla1, blaZ, blaTEM), mph for erythromycin resistance, rph for rifampicin resistance, and fosB for fosfomycin resistance. These genes were detected using ABRIcate and MEGARes 2.0 database, and their association with resistance phenotypes was analyzed.
Molecular Mechanisms of Drug Resistance in Staphylococcus aureus.
The paper discusses the molecular mechanisms of drug resistance in Staphylococcus aureus, focusing on beta-lactam, glycopeptide, oxazolidinone, MLS-B, aminoglycoside, and other resistance mechanisms. Key genes identified include blaZ, mecA, mecC, vanA, cfr, ermA, ermC, aac(6')-Ib, aph(3')-IIIa, and aadD. Mutations in pbp2 and pbp2a were also found to contribute to resistance.
Exploring the mobilome and resistome of Enterococcus faecium in a One Health context across two continents.
The study identifies various AMR genes in Enterococcus faecium, including vanA, vanB, ermB, ermT, ermA, aad(6), aph(3')-IIIa, aac(6')-Ie-aph(2')-Ia, sat-4, tetM, tet(W/N/W), dfrG, dfrF, lnuB, optrA, and lsaE, which are associated with different habitats and geographic locations.
Longitudinal Analysis of Antimicrobial Resistance among Enterococcus Species Isolated from Australian Beef Cattle Faeces at Feedlot Entry and Exit.
Virulence and antibiotic-resistance genes in Enterococcus faecalis associated with streptococcosis disease in fish.
The study identified various antibiotic-resistance genes in three strains of Enterococcus faecalis associated with streptococcosis in fish, including genes conferring resistance to tetracycline, macrolide-lincosamide-streptogramin, and vancomycin.
Antibiotic Susceptibility Profiling of Human Pathogenic Staphylococcus aureus Strains Using Whole Genome Sequencing and Genome-Scale Annotation Approaches.
The study identified several AMR genes in multidrug-resistant S. aureus strains, including blaZ, mecA, mecC, norA, norC, MgrA, tet(45), APH(3′)-IIIa, ermC, AAC(6′)-APH(2″), and fusC. These genes confer resistance to various antibiotics such as beta-lactams, fluoroquinolones, tetracyclines, aminoglycosides, macrolides, lincosamides, streptogramin B, and fusidic acid.
Heterotrophic bacteria in drinking water: evaluating antibiotic resistance and the presence of virulence genes.
The study identified a variety of antibiotic resistance genes in heterotrophic bacteria from drinking water, highlighting the presence of multidrug-resistant strains and the potential health risks associated with these bacteria.
Antimicrobial Resistance in Coagulase-Negative Staphylococci: Resistome, Mobiloome, and Relatedness
The study identifies multiple AMR genes and mutations in CoNS isolates from various hosts, highlighting the spread of multidrug resistance and the role of mobile genetic elements in the dissemination of resistance traits.
Colorectal cancer-associated Streptococcus gallolyticus: a hidden diversity expose.
The study identified multiple antibiotic resistance genes in Streptococcus gallolyticus subsp. gallolyticus (SGG) isolates associated with colorectal cancer, including aadE, ermB, aphA-3, and tetM, which confer resistance to streptomycin, macrolides/lincosamides/streptogramin B, kanamycin, and tetracycline, respectively.
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