Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline destructase Tet(49)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Tet(49) | Card DatabaseReference Gene CatalogResFinder Database | 5 | TETRACYCLINE, TETRACYCLINE ANTIBIOTIC | uncultured bacterium | - | 2015 | KR857683.1 | AKQ05893.1 |
| tet49 | Reslit | 2 | tetracycline | Legionella longbeachae +3 | - | 2018, 2022 | PDB:4a6n | - |
The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.
Research Article
The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.
Research Article
The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.
Research Article
The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.
Research Article
Tetracycline-Inactivating Enzymes.
Review
The paper reviews the structure, mechanism, and inhibition of tetracycline-destructase enzymes, highlighting their role in enzymatic inactivation of tetracyclines and the identification of new tetracycline destructase genes such as tetX, tetX1, tetX2, tet49, tet50, tet51, tet55, and tet56.
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
Research Article
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
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