Browse AMR Genes

Explore antimicrobial resistance genes from the literature

tet(52)

tetracycline destructase Tet(52)

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to tet(52)

Browse AMR rules for tet(52)

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Enzymatic inactivation
Validation Method: metagenomic analysis
Drug Classes: TETRACYCLINE, Tetracycline
Organisms: uncultured bacterium
Geographic Location: Amazon region
Alleles: 2
Papers: 2
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
Tet(52)	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	4	TETRACYCLINE, Tetracycline	uncultured bacterium	Amazon region	2015, 2022	KR857686.1

Papers2

1

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(52)
Allele: Tet(52)
Encodes: tetracycline destructase Tet(52)
Source Database: Reference Gene Catalog
Mechanism: Enzymatic inactivation
Confers Resistance To: TETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857686.1
Protein Accession: AKQ05896.1
Notes: ARO:3004587

2

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(52)
Allele: Tet(52)
Encodes: tetracycline destructase Tet(52)
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: TETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857686.1
Protein Accession: AKQ05896.1
Notes: ARO:3004587

3

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(52)
Allele: Tet(52)
Encodes: tetracycline destructase Tet(52)
Source Database: Card Database
Mechanism: Enzymatic inactivation
Confers Resistance To: TETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857686.1
Protein Accession: AKQ05896.1
Notes: ARO:3004587

4

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(52)
Allele: tet(52)
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: TETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857686

5

Impacts of soybean agriculture on the resistome of the Amazonian soil.

PMID 36160259 · 2022

The study identified numerous antibiotic and biocide resistance genes in Amazonian soils, with a focus on the impact of soybean agriculture. Key findings include the prevalence of resistance to tetracycline, cephalosporin, penam, fluoroquinolone, chloramphenicol, carbapenem, macrolide, and aminoglycoside antibiotics, along with resistance to heavy metals and biocides.

Gene Information

Gene Name: tet(52)
Allele: Tet(52)
Encodes: tetracycline inactivating enzyme
Source Database: Reslit
Confers Resistance To: Tetracycline
Geographic Location: Amazon region
Validation Method: metagenomic analysis

6

Gene Information

Gene Name: tet(52)
Allele: tet(52)
Encodes: tetracycline inactivation enzyme
Source Database: Card Database
Mechanism: antibiotic inactivation
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857686.1
Protein Accession: AKQ05896.1
Notes: ARO:3004587