Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline resistance ribosomal protection mosaic protein Tet(O/32/O)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Tet(O/32/O) | Reference Gene CatalogResFinder DatabaseReslit | 10 | MINOCYCLINE, TETRACYCLINE +2 | Clostridiaceae bacterium K10 +5 | United Kingdom, Poland, Denmark, Spain|Basque Country, Alberta, China, Germany|Vietnam, France |
| 2001, 2019, 2020, 2021, 2022, 2024, 2025 |
| AJ295238.3 |
| CAC41371.2 |
| tet(O/W/32/O/W/O) | Reslit | 1 | Tetracycline | Lactobacillus johnsonii | - | 2008 | AM889118|AM889122|AM710601|AM710605|DQ525023 | - |
| tet(O/W/32/O) | Reslit | 4 | Tetracycline | Streptococcus gallolyticus subsp. gallolyticus +5 | Italy, China | 2011, 2012, 2018, 2022 | FR824043|FR824044 | - |
| tet(O/32/O) | Card DatabaseResFinder Database | 2 | MINOCYCLINE, TETRACYCLINE +1 | Streptococcus suis, Clostridiaceae bacterium K10, Dorea longicatena AGR2136, Campylobacter jejuni subsp. jejuni 2008-894, Roseburia intestinalis XB6B4 +1 | - | 2013 | JQ740052, AJ295238, AUJS01000017, AIOQ01000025, FP929050, 48124 | CAC41371.2 |
| tet(O/W) | Reslit | 1 | Tetracycline | Limosilactobacillus reuteri | - | 2022 | - | - |
| tet(O)_3 | Reslit | 1 | Tetracycline | Campylobacter jejuni | Austria | 2023 | PRJNA558489 | - |
| tet(O/23/O) | Reslit | 1 | Tetracycline | Bifidobacterium | Cambodia | 2024 | - | - |
Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens.
Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens.
Mosaic Tetracycline Resistance Genes and Their Flanking Regions in Bifidobacterium thermophilum and Lactobacillus johnsonii.
The study identifies mosaic tetracycline resistance genes, including tet(W/32/O) and tet(O/W/32/O/W/O) in Bifidobacterium thermophilum and Lactobacillus johnsonii, as well as a third determinant, tet(L), in B. thermophilum.
Complete genome and comparative analysis of Streptococcus gallolyticus subsp. gallolyticus, an emerging pathogen of infective endocarditis.
The study identified tetracycline resistance genes tetL and tet(O/W/32/O) in the plasmid pSGG1 of Streptococcus gallolyticus subsp. gallolyticus strain BAA-2069, highlighting the role of plasmids in lateral gene transfer and tetracycline resistance.
Characterization of a Streptococcus suis tet(O/W/32/O)-carrying element transferable to major streptococcal pathogens.
The study identifies a novel mobile genetic element, 15K, carrying multiple antibiotic resistance genes including tet(O/W/32/O), erm(B), aadE, aphA, and tet(40), which can be transferred between major streptococcal pathogens.
Antimicrobial susceptibility, tetracycline and erythromycin resistance genes, and multilocus sequence typing of Streptococcus suis isolates from diseased pigs in China., Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens., Mosaic tetracycline resistance genes encoding ribosomal protection proteins.
Various Profiles of tet Genes Addition to tet(X) in Riemerella anatipestifer Isolates From Ducks in China.
The study identified and characterized multiple tetracycline resistance genes, including tet(A), tet(B), tet(M), tet(O), tet(O/W/32/O), tet(Q), and tet(X), in Riemerella anatipestifer isolates from ducks in China. The tet(X) gene was found to be the primary mechanism of tetracycline resistance.
Nationwide Stepwise Emergence and Evolution of Multidrug-Resistant Campylobacter jejuni Sequence Type 5136, United Kingdom.
The study identifies the emergence of multidrug-resistant Campylobacter jejuni sequence type 5136 in the UK, highlighting the role of specific AMR genes and mutations such as blaOXA-193, tet(O/32/O), aac3, and gyrA C257T in conferring resistance to various antibiotics.
Antimicrobial Resistance and Virulence-Associated Markers in Campylobacter Strains From Diarrheic and Non-diarrheic Humans in Poland.
The study identified several AMR genes, including blaOXA61, blaOXA184, tet(O), tet(O/32/O), aadE-Cc, and aph(3')-III, which confer resistance to beta-lactams, tetracyclines, and aminoglycosides in Campylobacter isolates. Additionally, mutations in the cmeR gene were linked to increased resistance to erythromycin, fluoroquinolones, and macrolides.
Prediction of antimicrobial resistance in clinical Campylobacter jejuni isolates from whole-genome sequencing data.
The study identified seven resistance genes and several mutations associated with antimicrobial resistance in Campylobacter jejuni isolates, demonstrating the effectiveness of whole-genome sequencing in predicting resistance.
Whole genome-based characterisation of antimicrobial resistance and genetic diversity in Campylobacter jejuni and Campylobacter coli from ruminants.
The study identified various AMR genes including aminoglycoside-modifying enzymes, tetracycline resistance genes, and beta-lactamases in Campylobacter jejuni and C. coli isolates from ruminants. Mutations in gyrA and rpsL were linked to quinolone and streptomycin resistance, respectively. The presence of specific genetic determinants correlated with phenotypic resistance.
Whole genome-based characterisation of antimicrobial resistance and genetic diversity in Campylobacter jejuni and Campylobacter coli from ruminants.
The study identified various AMR genes including aminoglycoside-modifying enzymes, tetracycline resistance genes, and beta-lactamases in Campylobacter jejuni and C. coli isolates from ruminants. Mutations in gyrA and rpsL were linked to quinolone and streptomycin resistance, respectively. The presence of specific genetic determinants correlated with phenotypic resistance.
Whole genome-based characterisation of antimicrobial resistance and genetic diversity in Campylobacter jejuni and Campylobacter coli from ruminants.
The study identified various AMR genes including aminoglycoside-modifying enzymes, tetracycline resistance genes, and beta-lactamases in Campylobacter jejuni and C. coli isolates from ruminants. Mutations in gyrA and rpsL were linked to quinolone and streptomycin resistance, respectively. The presence of specific genetic determinants correlated with phenotypic resistance.
Whole genome-based characterisation of antimicrobial resistance and genetic diversity in Campylobacter jejuni and Campylobacter coli from ruminants.
The study identified various AMR genes including aminoglycoside-modifying enzymes, tetracycline resistance genes, and beta-lactamases in Campylobacter jejuni and C. coli isolates from ruminants. Mutations in gyrA and rpsL were linked to quinolone and streptomycin resistance, respectively. The presence of specific genetic determinants correlated with phenotypic resistance.
New Sequence Types and Antimicrobial Drug-Resistant Strains of Streptococcus suis in Diseased Pigs, Italy, 2017-2019.
The study identified several AMR genes in Streptococcus suis isolates from diseased pigs in Italy, including ermb, tet(O), aac6-aph2, ant6-ia, aph3-iiia, spw, tet(40), tet(W), tet(O/W/32/O), tet(W/N/N), erm(47), lnuB, lsaE, and optrA, which confer resistance to various antibiotics such as erythromycin, tetracycline, gentamicin, lincomycin, and linezolid.
Genomic Characterization of Enterococcus hirae From Beef Cattle Feedlots and Associated Environmental Continuum.
The study identified several AMR genes in Enterococcus hirae isolates from beef cattle feedlots, including tetracycline resistance genes (tet(L), tet(M), tet(O), tet(S/M), tet(O/32/O)), macrolide resistance gene erm(B), and aminoglycoside resistance genes (aac(6')-Iid, ant(6)-Ia, aph(3')-III, sat4).
Genomic diversity of genus Limosilactobacillus.
The study identified 18 AMR genes in Limosilactobacillus species, primarily in L. reuteri from animal sources, including tetracycline, aminoglycoside, macrolide-lincosamide-streptogramin, and lincomycin resistance genes.
Withdrawal of antibiotic growth promoters in China and its impact on the foodborne pathogen Campylobacter coli of swine origin.
The study found that the withdrawal of antibiotic growth promoters in China led to an increase in antibiotic resistance in Campylobacter coli, particularly for gentamicin and florfenicol. Several resistance genes, including aadE-Cc, aac(6')-aph(2"), ant(6)-la, aph(3")-lll, aph(2")-lf, tet(O), tet(M), tet(O/32/O), cat, fexA, cfr(C), optrA, blaOXA-193, blaOXA-489, and blaOXA-61, were identified. Mutations in 23S rRNA and gyrA were also associated with resistance to erythromycin and ciprofloxacin, respectively.
Low-Level Tetracycline Resistance Gene tet(O)_3 in Campylobacter jejuni.
The study identifies a novel low-level tetracycline resistance gene, tet(O)_3, in two Campylobacter jejuni isolates from chicken meat. This gene is highly responsive to low tetracycline concentrations and shows similarity to a tet(O) gene in Streptococcus pneumoniae.
Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp.
The study identified 22 different resistance genes and gene variants, including erm(B), aph(3')-IIIa, aadE, catA, lnu(C), blaOXA, sat4, tet(O), and point mutations in gyrA, 23S rRNA, and rpsL, associated with antimicrobial resistance in thermotolerant Campylobacter spp.
Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp.
The study identified 22 different resistance genes and gene variants, including erm(B), aph(3')-IIIa, aadE, catA, lnu(C), blaOXA, sat4, tet(O), and point mutations in gyrA, 23S rRNA, and rpsL, associated with antimicrobial resistance in thermotolerant Campylobacter spp.
Faecal microbiota and cytokine profiles of rural Cambodian infants linked to diet and diarrhoeal episodes.
The study identified antimicrobial resistance genes such as erm(X), tet(O), tet(O/23/O), tet(Q), and tet(W) in Bifidobacterium isolates from Cambodian infants, highlighting the presence of resistance mechanisms in the gut microbiota.
Antimicrobial resistance pattern in Campylobacter strains isolated from both no-antibiotics-ever (NAE) and conventional broiler complexes: Genotypic and phenotypic characterization.
The study identified several AMR genes in Campylobacter strains from NAE and conventional broiler complexes, including bla OXA-61, bla OXA-184, tet (O), tet (O/32/O), and aph (3′)-III. These genes conferred resistance to various antibiotics such as tetracycline, cefoxitin, aztreonam, and gentamicin.
Commensal Clostridia in the preterm gut as reservoirs of antimicrobial resistance: susceptibility profiles, and resistance genes.
The study identifies tetracycline and clindamycin resistance genes (tet and erm) in various Clostridia species from preterm infants, highlighting their role as reservoirs of antimicrobial resistance.
Elucidation of population-based bacterial adaptation to antimicrobial treatment by single-cell sequencing analysis of the gut microbiome of a hospital patient.
The study identified 29 ARG subtypes across eight types in 13 known, five unknown, and 18 unclassified species, highlighting the complex and dynamic nature of antimicrobial resistance in the gut microbiome. Notably, the cfr(C) gene was detected in 11 bacterial species following antimicrobial treatment, with mutation patterns characterized in several species.
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