tet(S)

ribosomal protection protein

Validation StatusSupported

Overview

Validation Method: PCR and sequencing
Drug Classes: tetracycline
Organisms: Listeria monocytogenes, Enterococcus faecalis, Streptococcus pyogenes, Escherichia coli, Streptococcus lividans, Streptomyces rimosus, Streptococcus intermedius
Geographic Location: Europe
Papers: 3
Databases: Reslit

Papers3

Molecular ecology of tetracycline resistance: development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protection proteins.

PMID 11133424 · 2001

The study identified and characterized multiple tetracycline resistance genes encoding ribosomal protection proteins (RPPs) including tet(M), tet(O), tet(W), tet(Q), tet(S), tet(T), tetB(P), and otrA. These genes were detected in various bacterial species and environments, highlighting their prevalence and potential for horizontal gene transfer.

Gene Information

Gene Name: tet(S)
Allele: Tet(S)
Encodes: ribosomal protection protein
Source Database: Reslit
Confers Resistance To: tetracycline
Organisms Tested In: • Listeria monocytogenes
• Enterococcus faecalis
• Streptococcus pyogenes
• Escherichia coli
• Streptococcus lividans
• Streptomyces rimosus
Validation Method: PCR and sequencing
Sequence Accession: M85225|X56353|X04388|X75073|U08812|U58986|L12241|L12242|M21136|X90939|L09756|X92946|Y07780|M20925|M18896|AJ222769|Z21523|U73497|L33696|Y08615|X58717|L42544|L20800|M74049|X53401

Prevalence and molecular characterization of tetracycline resistance in Enterococcus isolates from food.

PMID 15006778 · 2004

The study identified tet(M), tet(L), and tet(S) genes as the primary tetracycline resistance mechanisms in Enterococcus isolates from food, with tet(M) being the most prevalent.

Gene Information

Gene Name: tet(S)
Allele: Tet(S)
Encodes: ribosomal protection protein
Source Database: Reslit
Confers Resistance To: tetracycline
Organisms Tested In: • Enterococcus faecalis
Geographic Location: Europe
Validation Method: PCR detection and MIC testing
Sequence Accession: AJ585076|AJ585077|AJ585078|AJ585079|AJ585080|AJ585081|AJ585082|AJ585083|AJ585084

Characterization of Tn916S, a Tn916-like element containing the tetracycline resistance determinant tet(S).

PMID 15205444 · 2004

The study characterizes Tn916S, a Tn916-like element containing the tetracycline resistance determinant tet(S).

Gene Information

Gene Name: tet(S)
Allele: Tet(S)
Encodes: ribosomal protection protein
Source Database: Reslit
Confers Resistance To: tetracycline
Organisms Tested In: • Streptococcus intermedius
• Enterococcus faecalis
• Escherichia coli
Validation Method: PCR and Southern hybridization
Sequence Accession: AY534326

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