Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline resistance protein
Overview
Identification of novel tetracycline resistance gene tet(X14) and its co-occurrence with tet(X2) in a tigecycline-resistant and colistin-resistant Empedobacter stercoris.
Research Article
A novel tetracycline resistance gene, tet(X14), was identified in a tigecycline-resistant and colistin-resistant Empedobacter stercoris strain. Overexpression of tet(X14) in E. coli increased tetracycline, tigecycline, and eravacycline MICs.
Source Tracking and Global Distribution of the Tigecycline Non-Susceptible tet(X).
Research Article
The study identifies novel tet(X) orthologs, including tet(X45), tet(X46), and tet(X47), which confer resistance to tigecycline and other tetracycline derivatives. It also traces the origins of tet(X) genes to Riemerella anatipestifer and highlights the role of Bacteroidaceae as a reservoir for these genes.
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