Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
biosynthetic gene cluster for tunicamycin
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| TM | Reslit | 1 | - | Streptomyces sp. strain fd1-xmd +1 | Shanghai | 2018 | CP019798 | - |
| tmexC1 | ResFinder Database |
| 1 |
| MINOCYCLINE, TETRACYCLINE +2 |
| Klebsiella pneumoniae |
| - |
| 2020 |
| MK347425 |
| - |
| tmexC | Reference Gene CatalogResFinder DatabaseReslit | 7 | MINOCYCLINE, TETRACYCLINE +4 | Klebsiella pneumoniae +4 | Ghana | 2020, 2021, 2023 | MK347425.1 | QHW08915.1 |
| tmexC2 | ResFinder DatabaseReslit | 2 | MINOCYCLINE, TETRACYCLINE +6 | Klebsiella ornithinolytica +1 | Europe | 2021, 2025 | MN175502 | - |
| tmexC3 | ResFinder Database | 1 | MINOCYCLINE, TETRACYCLINE +2 | Klebsiella aerogenes | - | 2021 | LC633285 | - |
| tmexC4 | ResFinder Database | 1 | MINOCYCLINE, TETRACYCLINE +2 | Enterobacter roggenkampii | - | 2022 | CP091084 | - |
Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp. strain fd1-xmd.
The study identifies the complete biosynthetic gene clusters for streptothricin (ST) and tunicamycin (TM) in Streptomyces sp. strain fd1-xmd through genome mining and experimental validation. The ST and TM gene clusters were successfully expressed in Streptomyces coelicolor M1146, confirming their roles in producing these bioactive compounds.
Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in Klebsiella pneumoniae.
Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in Klebsiella pneumoniae.
Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in Klebsiella pneumoniae.
A Novel Transferable Resistance-Nodulation-Division Pump Gene Cluster, tmexCD2-toprJ2, Confers Tigecycline Resistance in Raoultella ornithinolytica.
Characterization of TMexCD3-TOprJ3, an RND-Type Efflux System Conferring Resistance to Tigecycline in Proteus mirabilis, and Its Associated Integrative Conjugative Element.
A Transferable IncC-IncX3 Hybrid Plasmid Cocarrying bla(NDM-4), tet(X), and tmexCD3-toprJ3 Confers Resistance to Carbapenem and Tigecycline.
Emergence of a Novel Plasmid-Mediated Tigecycline Resistance Gene Cluster, tmexCD4-toprJ4, in Klebsiella quasipneumoniae and Enterobacter roggenkampii.
Taxonomic Assignment-Based Genome Reconstruction from Apical Periodontal Metagenomes to Identify Antibiotic Resistance and Virulence Factors.
The study identified several antibiotic resistance genes (ARGs) in metagenomic assemblies from apical periodontal infections, highlighting the presence of multidrug resistance mechanisms in Enterobacter and Pseudomonas species.
Antimicrobial Resistance in Wastewater Samples from Kumasi, Ghana: A Genomic and Metagenomic Analysis
The study identified several AMR genes and mutations in P. aeruginosa and K. pneumoniae isolates from wastewater samples in Kumasi, Ghana, highlighting the presence of multidrug-resistant strains carrying genes such as blaCTX-M-15, blaOXA-488, and qnrVC1, along with mutations in gyrA and parC contributing to fluoroquinolone resistance.
Pan-genome analysis of the Enterobacter hormaechei complex highlights its genomic flexibility and pertinence as a multidrug resistant pathogen.
The study identifies a wide range of antibiotic resistance genes in the Enterobacter hormaechei complex, highlighting its multidrug-resistant nature and the role of mobile genetic elements in the dissemination of resistance.
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