Browse AMR Genes

Explore antimicrobial resistance genes from the literature

tmexC1

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to tmexC1

Browse AMR rules for tmexC1

Overview

Drug Classes: Tigecycline
Organisms: Klebsiella pneumoniae
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
V175I	-	-	Klebsiella pneumoniae	Tigecycline	Reslit	Candidate

Papers1

1

Repurposing harmaline as a novel approach to reverse tmexCD1-toprJ1-mediated tigecycline resistance against klebsiella pneumoniae infections.

PMID 38790017 · 2024

Mutation Information

tmexC1: p.V175I

Protein Change: V175I
Organisms: Klebsiella pneumoniae
Confers Resistance To: Tigecycline
Source Database: Reslit