Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Membrane transporter TolA protein
Overview
Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.
The study identifies multiple genetic mutations in Salmonella enterica Typhimurium that contribute to biocide and antibiotic resistance, including changes in genes such as fabI, ftsK, yeaN, mipA, asnA, aarF, tolA, motB, tdcA, garA, and bigA.
Proteomic Analysis of Resistance of Gram-Negative Bacteria to Chlorhexidine and Impacts on Susceptibility to Colistin, Antimicrobial Peptides, and Ceragenins.
The study identifies several genes upregulated in chlorhexidine-resistant Pseudomonas aeruginosa, including OprF, LptD, TolB, TolA, MurD, PagL, LpxD, LpxC, LolA, BamD, OprI, ClpB, SecG, SecB, MexA, AceE, AceF, AccD, AccB, FadA, FabV, AcpP1, sucC, SucD, FumC1, Mqo2, GltA, AcnA, AcnB, PilA, PilG, PilH, PilJ, and PilQ, which are associated with membrane modification, stress response, protein transport, efflux pump, metabolic adaptation, and adhesion and motility.
Acidic Microenvironment Determines Antibiotic Susceptibility and Biofilm Formation of Pseudomonas aeruginosa.
The study shows that acidic pH increases antibiotic tolerance and resistance in Pseudomonas aeruginosa, primarily through mutations in efflux pump genes (mexB, mexR) and other genes involved in biofilm formation and virulence.
The intrinsic macrolide resistome of Escherichia coli.
The study identified several genes involved in intrinsic macrolide resistance in E. coli, including surA, waaG, acrA, acrB, tolC, lptC, bamB, lpp, tolA, tolB, tolR, waaQ, gmhB, galU, waaP, lapC, prc, nlpI, hrpA, and pgm. These genes are associated with outer membrane integrity, efflux pumps, LPS biosynthesis, and peptidoglycan metabolism.
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