Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Potassium transporter
Overview
| Candidate |
| P151S | - | - | Escherichia coli | Gentamicin | Reslit | Candidate |
| T350K | - | decreases the uptake of aminoglycoside antibiotics | Escherichia coli, Salmonella enterica | Kanamycin|Tobramycin|Streptomycin | Reslit | Candidate |
Genetic architecture of intrinsic antibiotic susceptibility.
The study identifies multiple genes and mutations that contribute to antibiotic tolerance in E. coli, revealing a large mutational target size for increasing drug resistance. Key findings include the role of genes involved in electron transport, flagella synthesis, and efflux pumps in modulating susceptibility to various antibiotics.
Evolution of high-level resistance during low-level antibiotic exposure.
High-level streptomycin resistance in Salmonella enterica evolved through combinations of five mutations: gidB, trkH, nuoG, cyoB, and znuA, along with the aadA gene. These mutations collectively enhance resistance through altered ribosomal targets, reduced drug uptake, and enzymatic modification.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research