tyrS

tyrosyl-tRNA synthetase

Validation StatusCandidate

Overview

Mechanism: enhanced expression due to riboswitch mutations
Validation Method: mutant analysis and transcriptional fusion
Organisms: Bacillus subtilis
Papers: 1
Databases: Reslit
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	C-38T	-	Bacillus subtilis	-	Reslit	Candidate

Papers1

Identification and characterization of mutations conferring resistance to D-amino acids in Bacillus subtilis.

PMID 25733611 · 2015

The study identifies mutations in the tyrS gene that confer resistance to d-Tyr in Bacillus subtilis by enhancing tyrS expression or improving the stereoselectivity of TyrRS.

Gene Information

Gene Name: tyrS
Allele: tyrS
Encodes: tyrosyl-tRNA synthetase
Source Database: Reslit
Mechanism: enhanced expression due to riboswitch mutations
Organisms Tested In: • Bacillus subtilis
Validation Method: mutant analysis and transcriptional fusion

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tyrS

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