Browse AMR Genes

Explore antimicrobial resistance genes from the literature

uL3

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to uL3

Browse AMR rules for uL3

Overview

Drug Classes: Pleuromutilin
Organisms: Thermus thermophilus
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
R144H	-	single resistance variant	Thermus thermophilus	Pleuromutilin	Card Database	Established
R144C	-	single resistance variant	Thermus thermophilus	Pleuromutilin	Card Database	Established

Papers1

1

Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus.

PMID 32526926 · 2020

Thermus thermophilus uL3 mutations conferring resistance to pleuromutilin antibiotics; CARD accession: CARD:3005081

Mutation Information

uL3: p.R144H uL3: p.R144C

Protein Change: R144H, R144C
Organisms: Thermus thermophilus
Confers Resistance To: Pleuromutilin
Effect on Function: single resistance variant
Source Database: Card Database