vanB
glycopeptide resistance
Overview
- Drug Classes
- vancomycin
- Organisms
- Enterococcus faecium, Enterococcus faecalis, Clostridium hathewayi +3 more
- Papers
- 5
vanA and vanB incorporate into an endemic ampicillin-resistant vancomycin-sensitive Enterococcus faecium strain: effect on interpretation of clonality.
PMID 10565910 · 1999The study characterizes the incorporation of vanA and vanB genes into an endemic ampicillin-resistant vancomycin-sensitive Enterococcus faecium strain, highlighting their role in vancomycin resistance.
Gene Information
- Gene Name
- vanB
- Allele
- VanB
- Encodes
- glycopeptide resistance
- Validation Method
- multiplex PCR and hybridization with vanB probe
Confers Resistance To
Organisms Tested In
Isolation Details
Antimicrobial Resistance Mechanisms and Molecular Detection Techniques
PMID 11585788 · 2023The paper discusses molecular detection methods for antimicrobial resistance, focusing on genes like mecA and blaZ, which confer resistance to beta-lactam antibiotics in staphylococci.
Gene Information
- Gene Name
- vanB
- Allele
- VanB
- Encodes
- d-Ala-d-Ala ligase
- Validation Method
- PCR and sequencing
Confers Resistance To
Organisms Tested In
Isolation Details
Impact of elements containing glycopeptide resistance genes on expression of virulence in Enterococcus faecalis peritonitis: a pilot study with rats.
PMID 12709322 · 2003The study investigated the impact of glycopeptide resistance genes vanA and vanB on the virulence of Enterococcus faecalis in a rat peritonitis model. Both vanA and vanB conferred resistance to vancomycin.
Gene Information
- Gene Name
- vanB
- Allele
- VanB
- Encodes
- glycopeptide resistance
- Validation Method
- susceptibility testing
Confers Resistance To
Organisms Tested In
Nosocomial infection with vancomycin-dependent enterococci.
PMID 15324549 · 2004The study characterizes vancomycin-dependent enterococci (VDE) and identifies the presence of vanA and vanB genes in these isolates, indicating their resistance to vancomycin.
Gene Information
- Gene Name
- vanB
- Allele
- VanB
- Encodes
- vancomycin resistance determinant
- Validation Method
- polymerase chain reaction to amplify sequences coding for resistance
Confers Resistance To
Organisms Tested In
Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci: interference by vanB-containing anaerobic bacilli.
PMID 15616278 · 2005The study evaluated PCR primer sets for detecting the vanB gene in fecal samples and found that vanB-containing anaerobic bacilli can cause false positives for vancomycin-resistant enterococci (VRE).
Gene Information
- Gene Name
- vanB
- Allele
- VanB
- Encodes
- glycopeptide resistance
- Validation Method
- PCR and sequencing
Confers Resistance To
Organisms Tested In
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