vanF
d-Ala:d-Lac ligase
NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to vanF
AMR Rules
Browse AMR rules for vanF
Validation StatusCandidate
Overview
- Validation Method
- experimental validation via sequencing and phenotypic analysis
- Drug Classes
- vancomycin
- Organisms
- Paenibacillus popilliae, Paenibacillus lentimorbus
- Papers
- 1
- Databases
- Reslit
Papers1
1
Putative VanRS-like two-component regulatory system associated with the inducible glycopeptide resistance cluster of Paenibacillus popilliae.
The study identifies a putative glycopeptide resistance cluster in Paenibacillus popilliae, including the vanF gene encoding a d-Ala:d-Lac ligase and a VanRS-like two-component regulatory system, suggesting a mechanism for inducible vancomycin resistance.
Gene Information
- Gene Name
- vanF
- Allele
- VanF
- Encodes
- d-Ala:d-Lac ligase
- Source Database
- Reslit
- Confers Resistance To
- vancomycin
- Organisms Tested In
- • Paenibacillus popilliae• Paenibacillus lentimorbus
- Validation Method
- experimental validation via sequencing and phenotypic analysis
- Sequence Accession
- AF155139|AF432144|AF098802
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