vanR-A

regulator

Overview

Validation Method
cloning and MIC testing
Drug Classes
glycopeptides
Organisms
Enterococcus faecium BM4339
Papers
1
Databases
Reslit
Papers1
1

Characterization of the vanD glycopeptide resistance gene cluster from Enterococcus faecium BM4339.

PMID 10368136 · 1999

The study characterizes the vanD glycopeptide resistance gene cluster in Enterococcus faecium BM4339, identifying several genes including vanD, vanH, vanX, vanY, vanR, and vanS, which collectively confer resistance to glycopeptide antibiotics through the synthesis of d-alanyl-d-lactate-terminating peptidoglycan precursors.

Gene Information

Gene Name
vanR-A
Allele
vanR
Encodes
regulator
Source Database
Reslit
Confers Resistance To
glycopeptides
Organisms Tested In
Enterococcus faecium BM4339
Validation Method
cloning and MIC testing
Sequence Accession
AF130997|AF130998
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