vanR-C
response regulator
Overview
- Validation Method
- cloning and sequence analysis
- Drug Classes
- vancomycin
- Organisms
- Enterococcus casseliflavus ATCC 25788, Enterococcus gallinarum
- Geographic Location
- France|United Kingdom
- Alleles
- 2
- Papers
- 2
- Databases
- Reslit
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| vanR C-2 | Reslit | 1 | vancomycin | Enterococcus casseliflavus ATCC 25788 | - | 2002 | AY033089 | - |
| vanR_C | Reslit | 1 | vancomycin | Enterococcus gallinarum | France|United Kingdom | 2005 | AF162694|J01859 | - |
Biochemical and genetic characterization of the vanC-2 vancomycin resistance gene cluster of Enterococcus casseliflavus ATCC 25788.
The study characterizes the vanC-2 gene cluster in Enterococcus casseliflavus ATCC 25788, identifying genes involved in vancomycin resistance, including vanC-2, vanXY C-2, vanT C-2, vanR C-2, and vanS C-2. These genes contribute to the production of cell wall precursors that replace d-alanine with d-serine, reducing vancomycin binding.
Gene Information
- Gene Name
- vanR-C
- Allele
- vanR C-2
- Encodes
- response regulator
- Source Database
- Reslit
- Confers Resistance To
- vancomycin
- Organisms Tested In
- • Enterococcus casseliflavus ATCC 25788
- Validation Method
- cloning and sequence analysis
- Sequence Accession
- AY033089
Transcriptional analysis of the vanC cluster from Enterococcus gallinarum strains with constitutive and inducible vancomycin resistance.
The study characterizes the vanC cluster in Enterococcus gallinarum strains with constitutive and inducible vancomycin resistance, identifying key genes and mutations involved in glycopeptide resistance mechanisms.
Gene Information
- Gene Name
- vanR-C
- Allele
- vanR_C
- Encodes
- protein exhibiting structural homology with members of two component regulatory systems
- Source Database
- Reslit
- Confers Resistance To
- vancomycin
- Organisms Tested In
- • Enterococcus gallinarum
- Geographic Location
- France|United Kingdom
- Validation Method
- transcriptional analysis and sequence comparison
- Sequence Accession
- AF162694|J01859
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