Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
sensor histidine kinase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| S313F | - | - | Clostridioides difficile | vancomycin | Reslit | Candidate |
| T349I | - | - | Clostridioides difficile | vancomycin | Reslit | Supported |
| D168Y | - | - | - | teicoplanin | Reslit | Candidate |
| E221G | - | - | - | teicoplanin | Reslit | Candidate |
| S232F | - | - | - | vancomycin | Reslit | Candidate |
| S232Y | - | - | - | vancomycin | Reslit | Candidate |
| T237K | - | - | - | vancomycin | Reslit | Candidate |
| T237M | - | - | - | vancomycin | Reslit | Candidate |
| E247K | - | - | - | vancomycin | Reslit | Candidate |
| R200L | - | - | - | vancomycin | Reslit | Candidate |
| D312N | - | - | - | vancomycin | Reslit | Candidate |
| D312A | - | - | - | vancomycin | Reslit | Candidate |
| G320S | - | - | - | vancomycin | Reslit | Candidate |
| A30G | - | - | - | teicoplanin | Reslit | Candidate |
| L50V | - | - | - | teicoplanin | Reslit | Candidate |
| E54Q | - | - | - | teicoplanin | Reslit | Candidate |
| Q69H | - | - | - | teicoplanin | Reslit | Candidate |
| R334L | constitutive or partly constitutive expression of the vanG operon | Clostridioides difficile | vancomycin | Reslit | Candidate | |
| - | - | Streptomyces coelicolor | vancomycin | Reslit | Candidate | |
| - | - | Streptomyces coelicolor | vancomycinteicoplanin | Reslit | Candidate |
Mechanisms of antibiotic resistance of Clostridioides difficile.
Review
Regulation of Resistance in Vancomycin-Resistant Enterococci: The VanRS Two-Component System.
Review
Genetic determinants of resistance to antimicrobial therapeutics are rare in publicly available Clostridioides difficile genome sequences.
Research Article
Detected in 3477 genomes
Reference Susceptibility Testing and Genomic Surveillance of Clostridioides difficile, United States, 2012-17.
Research Article
VanG- and D-Ala-D-Ser-dependent peptidoglycan synthesis and vancomycin resistance in Clostridioides difficile.
Research Article
causes constitutive or partly constitutive expression of vanG operon
Genome sequencing analysis of Streptomyces coelicolor mutants that overcome the phosphate-depending vancomycin lethal effect.
Research Article