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Explore antimicrobial resistance genes from the literature
membrane-bound serine racemase VanT-E
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| VanT-E | Card DatabaseReference Gene Catalog | 2 | VANCOMYCIN | Enterococcus faecalis | - | 2002 | FJ872411.1 | AAL27444.1 |
| vanTE |
Reslit |
| 1 |
| Glycopeptide |
| Enterococcus faecalis BM4405 +2 |
| - |
| 2005 |
| - |
| - |
Molecular characterization of the vanE gene cluster in vancomycin-resistant Enterococcus faecalis N00-410 isolated in Canada.
Molecular characterization of the vanE gene cluster in vancomycin-resistant Enterococcus faecalis N00-410 isolated in Canada.
Silencing of glycopeptide resistance in Enterococcus faecalis BM4405 by novobiocin.
The study identified mutations in the vanE operon and gyrB gene of Enterococcus faecalis BM4405-1, which led to silencing of glycopeptide resistance. The vanE operon, including vanE, vanXYE, and vanTE, was found to confer vancomycin resistance when cloned into a susceptible strain. The mutation in gyrB (K337Y) was linked to altered DNA supercoiling and reduced expression of the vanE operon.
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