Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
D-Ala-D-Ala dipeptidase/D-Ala-D-Ala carboxypeptidase VanXY-E
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| VanXY-E | Card DatabaseReference Gene Catalog | 2 | VANCOMYCIN | Enterococcus faecalis | - | 2002 | FJ872411.1 | AAL27443.1 |
| vanXY_in_vanE | Card Database | 1 | GLYCOPEPTIDE ANTIBIOTIC, VANCOMYCIN | Enterococcus faecalis | - | - | FJ872411.1 | AAL27443.1 |
| vanXYE | Reslit | 1 | glycopeptides | Enterococcus faecalis BM4405 +2 | - | 2005 | - | - |
Molecular characterization of the vanE gene cluster in vancomycin-resistant Enterococcus faecalis N00-410 isolated in Canada.
Research Article
Molecular characterization of the vanE gene cluster in vancomycin-resistant Enterococcus faecalis N00-410 isolated in Canada.
Research Article
Silencing of glycopeptide resistance in Enterococcus faecalis BM4405 by novobiocin.
Research Article
The study identified mutations in the vanE operon and gyrB gene of Enterococcus faecalis BM4405-1, which led to silencing of glycopeptide resistance. The vanE operon, including vanE, vanXYE, and vanTE, was found to confer vancomycin resistance when cloned into a susceptible strain. The mutation in gyrB (K337Y) was linked to altered DNA supercoiling and reduced expression of the vanE operon.
No comments yet. Be the first to comment!