vanY-A

dd-carboxypeptidase

Overview

Drug Classes
glycopeptides
Organisms
Enterococcus faecium BM4339
Papers
1
Papers1
1

Characterization of the vanD glycopeptide resistance gene cluster from Enterococcus faecium BM4339.

PMID 10368136 · 1999

The study characterizes the vanD glycopeptide resistance gene cluster in Enterococcus faecium BM4339, identifying several genes including vanD, vanH, vanX, vanY, vanR, and vanS, which collectively confer resistance to glycopeptide antibiotics through the synthesis of d-alanyl-d-lactate-terminating peptidoglycan precursors.

Gene Information

Gene Name
vanY-A
Allele
vanY
Encodes
dd-carboxypeptidase
Validation Method
cloning and MIC testing

Confers Resistance To

glycopeptides

Organisms Tested In

Enterococcus faecium BM4339
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