Browse AMR Genes

Explore antimicrobial resistance genes from the literature

VanY-M

glycopeptide resistance gene cluster;vanY

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to VanY-M

Browse AMR rules for VanY-M

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic target alteration
Drug Classes: GLYCOPEPTIDE ANTIBIOTIC, VANCOMYCIN
Organisms: Enterococcus faecium
Alleles: 2
Papers: 2
Databases: Card DatabaseReference Gene Catalog

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
vanY_in_vanM_cl	Card Database	1	GLYCOPEPTIDE ANTIBIOTIC	Enterococcus faecium	-	-	FJ349556.1	ACL82959.1
VanY-M	Reference Gene Catalog	1	VANCOMYCIN	Enterococcus faecium	-	2020	CP038995.1	QHQ83279.1

Papers2

1

Gene Information

Gene Name: VanY-M
Allele: vanY_in_vanM_cl
Encodes: glycopeptide resistance gene cluster;vanY
Source Database: Card Database
Mechanism: antibiotic target alteration
Confers Resistance To: GLYCOPEPTIDE ANTIBIOTIC
Organisms Tested In: • Enterococcus faecium
Sequence Accession: FJ349556.1
Protein Accession: ACL82959.1
Notes: ARO:3002961

2

Tandem amplification of the vanM gene cluster drives vancomycin resistance in vancomycin-variable enterococci.

Research Article

PMID 31742612 · 2020

Gene Information

Gene Name: vanY-M
Allele: VanY-M
Encodes: D-Ala-D-Ala carboxypeptidase VanY-M
Source Database: Reference Gene Catalog
Confers Resistance To: VANCOMYCIN
Organisms Tested In: • Enterococcus faecium
Sequence Accession: CP038995.1
Protein Accession: QHQ83279.1

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