vanb2
glycopeptide resistance
Overview
- Validation Method
- characterization of transposon Tn1549
- Drug Classes
- vancomycin
- Organisms
- Enterococcus spp., Enterococcus faecium, Enterococcus faecalis
- Geographic Location
- Scotland, Taiwan
- Papers
- 3
- Databases
- Reslit
Characterization of transposon Tn1549, conferring VanB-type resistance in Enterococcus spp.
The study characterizes the transposon Tn1549, which confers VanB-type glycopeptide resistance in Enterococcus spp., highlighting the vanB2 operon as the key element responsible for vancomycin resistance.
Gene Information
- Gene Name
- vanb2
- Allele
- vanB2
- Encodes
- glycopeptide resistance
- Source Database
- Reslit
- Confers Resistance To
- vancomycin
- Organisms Tested In
- • Enterococcus spp.
- Validation Method
- characterization of transposon Tn1549
- Sequence Accession
- AJ192329
Identification and characterization of vanB2 glycopeptide resistance elements in enterococci isolated in Scotland.
The study identifies and characterizes the vanB2 glycopeptide resistance element in Enterococcus faecium and Enterococcus faecalis isolates from Scotland, demonstrating its prevalence and genetic differences from vanB1.
Gene Information
- Gene Name
- vanb2
- Allele
- vanB2
- Encodes
- glycopeptide resistance element
- Source Database
- Reslit
- Confers Resistance To
- vancomycin
- Organisms Tested In
- • Enterococcus faecium• Enterococcus faecalis
- Geographic Location
- Scotland
- Validation Method
- PCR and sequencing
- Sequence Accession
- AJ272437|AJ272436
High prevalence of VanB2 vancomycin-resistant Enterococcus faecium in Taiwan.
The study identified the vanB2 gene cluster as the primary cause of vancomycin resistance in Enterococcus faecium isolates in Taiwan, with sequence variations observed among the isolates.
Gene Information
- Gene Name
- vanb2
- Allele
- vanB2
- Encodes
- d-Ala–d-Lac ligase
- Source Database
- Reslit
- Confers Resistance To
- vancomycin
- Organisms Tested In
- • Enterococcus faecium
- Geographic Location
- Taiwan
- Validation Method
- PCR amplification and DNA sequencing
- Sequence Accession
- AF310956|AF310953|AF310954|AF310957
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