vand4

d-Ala-d-Lac ligase

Overview

Mechanism
production of d-Ala-d-Lac ligase
Validation Method
sequencing and functional analysis
Drug Classes
glycopeptides
Organisms
Enterococcus faecium
Geographic Location
Brazil
Papers
1
Databases
Reslit
Papers1
1

Characterization of a Divergent vanD-Type Resistance Element from the First Glycopeptide-Resistant Strain of Enterococcus faecium Isolated in Brazil.

PMID 11083656 · 2000

The study characterizes a novel vanD allele, vanD4, responsible for glycopeptide resistance in a Brazilian strain of Enterococcus faecium.

Gene Information

Gene Name
vand4
Allele
vanD4
Encodes
d-Ala-d-Lac ligase
Source Database
Reslit
Mechanism
production of d-Ala-d-Lac ligase
Confers Resistance To
glycopeptides
Organisms Tested In
Enterococcus faecium
Geographic Location
Brazil
Validation Method
sequencing and functional analysis
Sequence Accession
AF277571
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