Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
VarG family subclass B1-like metallo-beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| varG | Reference Gene CatalogReslit | 8 | CARBAPENEM, Penicillin +4 | Vibrio cholerae +5 | Norway, China | 2017, 2020, 2022, 2023, 2024 | CP024867.1 |
| AVL22772.1 |
| Vcho_varG | Card Database | 1 | - | Vibrio cholerae O1 biovar El Tor str. N16961 | - | - | AE003852.1 | AAF94716.1 |
The Vibrio cholerae var regulon encodes a metallo-β-lactamase and an antibiotic efflux pump, which are regulated by VarR, a LysR-type transcription factor.
The Vibrio cholerae var regulon encodes a metallo-β-lactamase and an antibiotic efflux pump, which are regulated by VarR, a LysR-type transcription factor.
The study identified VarG as a metallo-β-lactamase capable of hydrolyzing various β-lactam antibiotics, including carbapenems, and VarABCDEF as an antibiotic efflux pump that confers resistance to macrolides. These genes are regulated by VarR, a LysR-type transcription factor.
Vibrios from the Norwegian marine environment: Characterization of associated antibiotic resistance and virulence genes.
The study identified various antibiotic resistance genes in Vibrio isolates from the Norwegian marine environment, including beta-lactamases (blaCARB, blaampC, varG), tetracycline resistance genes (tet34, tet35), a multidrug efflux pump (adeF), a quinolone resistance gene (qnr), and a chloramphenicol resistance gene (catB-related).
Genome- and Proteome-Wide Analysis of Lysine Acetylation in Vibrio vulnificus Vv180806 Reveals Its Regulatory Roles in Virulence and Antibiotic Resistance.
The study identifies varG, tet(34), and tet(35) as antibiotic resistance genes in Vibrio vulnificus Vv180806, with varG showing beta-lactamase activity against penicillins, carbapenems, and cephalosporins, contributing to cefoxitin resistance.
Identification and whole-genome sequencing analysis of Vibrio vulnificus strains causing pearl gentian grouper disease in China.
The study identified Vibrio vulnificus EPL 0201 biotype 2 as a multidrug-resistant strain with high pathogenicity, possessing virulence factors vvhA, rtxA, and wza, as well as resistance genes such as H-NS, TEM-1, sul1, tet, floR, parE, mprF, APH(6)-Id, APH(3'')-Ib, aadA16, and arr-3.
Complete genome sequence and comparative analysis of a Vibrio vulnificus strain isolated from a clinical patient.
Potential involvement of beta-lactamase homologous proteins in resistance to beta-lactam antibiotics in gram-negative bacteria of the ESKAPEE group.
The study identifies and characterizes beta-lactamase homologous proteins in gram-negative bacteria of the ESKAPEE group, highlighting their potential role in resistance to beta-lactam antibiotics.
Loop-mediated isothermal amplification assays for the detection of antimicrobial resistance elements in Vibrio cholera.
The study presents LAMP assays targeting AMR genes in Vibrio cholerae, including aph(6), varG, floR, qnrVC5, and almG, which confer resistance to aminoglycosides, penicillins/carbapenems, phenicol antibiotics, fluoroquinolones, and polymyxins, respectively.
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