Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ABC-F type ribosomal protection protein Vga(C)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Vga(C) | Card DatabaseReference Gene CatalogResFinder Database | 4 | VIRGINIAMYCIN M, CLINDAMYCIN +5 | Staphylococcus aureus subsp. aureus ST398 +1 | - | 2006, 2010 | FN377602.2 | CAY33094.2 |
| vgaC | Card DatabaseReslit | 8 | streptogramin a, lincosamides +13 | Staphylococcus aureus +3 | Germany, Germany|United Kingdom|Ireland|France|Malta|Abu Dhabi|Hong Kong|Australia|Trinidad & Tobago|United States|Italy|Spain|Portugal|Switzerland|Canada|Middle East|USA|Asia|UK, global, China, Europe | 2009, 2011, 2019, 2020, 2023 | FN377602 | CBL58195.1 |
A new evolutionary variant of the streptogramin A resistance protein, Vga(A)LC, from Staphylococcus haemolyticus with shifted substrate specificity towards lincosamides.
Research Article
A new evolutionary variant of the streptogramin A resistance protein, Vga(A)LC, from Staphylococcus haemolyticus with shifted substrate specificity towards lincosamides.
Research Article
A new evolutionary variant of the streptogramin A resistance protein, Vga(A)LC, from Staphylococcus haemolyticus with shifted substrate specificity towards lincosamides.
Research Article
Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain.
Research Article
The study identifies a novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain, which confers resistance to streptogramin A antibiotics, lincosamides, and pleuromutilins.
Small plasmids carrying vga(A) or vga(C) genes mediate resistance to lincosamides, pleuromutilins and streptogramin A antibiotics in methicillin-resistant Staphylococcus aureus ST398 from swine.
Research Article
A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus.
Research Article
The study characterizes various methicillin-resistant Staphylococcus aureus (MRSA) clones, highlighting their antimicrobial resistance and virulence-associated markers, with a focus on SCC mec types and PVL status.
Antimicrobial Resistance in Staphylococci of Animal Origin
Review
The paper discusses various antimicrobial resistance genes and mutations in staphylococci of animal origin, highlighting their roles in resistance to multiple antibiotics such as macrolides, lincosamides, streptogramins, oxazolidinones, and others. Key genes include erm, msr, mph, ere, lnu, vga, cfr, optrA, dfr, fus, ileS2, blaZ, aadD, ble, fosD, fosB, czrC, and qac genes, which confer resistance to specific antibiotics and are prevalent in different staphylococcal species.
Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study.
Research Article
The study identified several AMR genes using Nanopore sequencing, including mecA, blaTEM-4, blaTEM-112, blaTEM-157, blaACT-5, oqxB, tetC, ermA, erm (33), tet38, ant(4′)-lb, tetK, tetQ, sul1, dfrA, acrF, parE, mfd, mphA, aadA5, vgaC, blaACT-5, blaACT-14, mefA, mel, tetX, tetM, isaC, and aadA5, which conferred resistance to various antibiotics such as methicillin, ticarcillin, ceftazidime, erythromycin, clindamycin, tetracycline, trimethoprim-sulfamethoxazole, ciprofloxacin, and levofloxacin.
Metadata Analysis of mcr-1-Bearing Plasmids Inspired by the Sequencing Evidence for Horizontal Transfer of Antibiotic Resistance Genes Between Polluted River and Wild Birds.
Research Article
The study identifies the mcr-1 gene as a key factor in colistin resistance in E. coli strains isolated from polluted rivers and wild birds. It also characterizes several other AMR genes including aadA1, aadA2, aph(3′)-Ia, aph(3″)-Ib, aph(4)-Ia, aph(6)-Id, tet(B), tet(D), tet(A), bla CTX–M–14, bla TEM–1, qnrS2, oqxA, oqxB, cmlA1, floR, vgaC, sul1, sul2, sul3, dfrA12, and glpT (E448K).
Fecal Klebsiella pneumoniae Carriage Is Intermittent and of High Clonal Diversity.
Research Article
The study identified 25 antibiotic resistance genes in 80 Klebsiella pneumoniae isolates, primarily encoding efflux pumps and inactivating enzymes. Notably, blaSHV, emrB, emrR, marA, marR, msbA, ompK37, oqxA, oqxB, acrA, vgaC, fosA, tet(D), APH(3")-Ib, APH(6)-Id, aadA, qnrS2, rpoB2, mexF, and oprN were found to confer resistance to various antibiotics.
Genomic Diversity of Methicillin-Resistant Staphylococcus aureus CC398 Isolates Collected from Diseased Swine in the German National Resistance Monitoring Program GERM-Vet from 2007 to 2019.
Research Article
The study identified numerous antimicrobial resistance (AMR) genes in methicillin-resistant Staphylococcus aureus (MRSA) CC398 isolates from diseased swine in Germany, including beta-lactam, tetracycline, macrolide, lincosamide, streptogramin B, phenicol, aminoglycoside, and fluoroquinolone resistance genes. These genes were often located on small transposons or plasmids, contributing to the multidrug resistance profile of the isolates.
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