vga(a)v
ATP-binding cassette (ABC) transporter
NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to vga(a)v
AMR Rules
Browse AMR rules for vga(a)v
Curation StatusNot Validated
Overview
- Drug Classes
- streptogramin a (sga), lincosamides
- Organisms
- Staphylococcus aureus, Staphylococcus epidermidis
- Papers
- 1
Papers1
1
Molecular analysis of resistance to streptogramin A compounds conferred by the Vga proteins of staphylococci.
PMID 15728891 · 2005The study identifies and characterizes the Vga proteins, including vga(A), vga(A)v, vga(B), and Lmo0919, as conferring resistance to streptogramin A (SGA) and lincosamides in staphylococci. It also shows that vga(B) increases resistance to pristinamycin, a combination of SGA and SGB.
Gene Information
- Gene Name
- vga(a)v
- Allele
- vga(A)v
- Encodes
- ATP-binding cassette (ABC) transporter
- Validation Method
- cloning in staphylococci and MIC testing
Confers Resistance To
streptogramin a (sga)lincosamides
Organisms Tested In
• Staphylococcus aureus
• Staphylococcus epidermidis
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