vncS

histidine kinase

Validation StatusCandidate

Overview

Mechanism: mutation in vncS gene leads to vancomycin tolerance
Validation Method: sequencing and functional assays
Drug Classes: Vancomycin
Organisms: Streptococcus pneumoniae
Geographic Location: Korea
Papers: 1
Databases: Reslit

Papers1

Vancomycin-tolerant Streptococcus pneumoniae in Korea.

PMID 17021077 · 2006

The study identified two vancomycin-tolerant Streptococcus pneumoniae strains, S3 and H8, with specific mutations in the vncS and vex2 genes that contribute to vancomycin tolerance.

Gene Information

Gene Name: vncS
Allele: vncS
Encodes: histidine kinase
Source Database: Reslit
Mechanism: mutation in vncS gene leads to vancomycin tolerance
Confers Resistance To: Vancomycin
Organisms Tested In: • Streptococcus pneumoniae
Geographic Location: Korea
Validation Method: sequencing and functional assays

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vncS

Gene Information