Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
putative membrane protein
Overview
| Candidate |
| V199A | - | - | Staphylococcus aureus | Nafcillin | Reslit | Candidate |
| P126S | - | - | Staphylococcus aureus | Nafcillin | Reslit | Candidate |
| A152V | - | - | Staphylococcus aureus | Vancomycin | Reslit | Candidate |
| E156G | - | - | Staphylococcus aureus | Vancomycin | Reslit | Candidate |
VraT/YvqF is required for methicillin resistance and activation of the VraSR regulon in Staphylococcus aureus.
The study identifies VraT as a critical component of the VraSR regulon required for methicillin resistance in Staphylococcus aureus, demonstrating that its deletion reduces resistance and that its complementation restores resistance.
Rapid resistance development to three antistaphylococcal therapies in antibiotic-tolerant staphylococcus aureus bacteremia.
The study identifies mutations in mprF, vraT, tagH, agrB, and saeR that contribute to daptomycin and vancomycin resistance in Staphylococcus aureus. These mutations were experimentally validated through whole genome sequencing and phenotypic characterization.
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