vrade

ABC transporter

Validation StatusCandidate

Overview

Mechanism: resistance to bacitracin
Validation Method: mutant analysis and MIC testing
Drug Classes: Bacitracin
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance.

PMID 19751498 · 2009

The study identifies vraDE and vraSR as critical components in Staphylococcus aureus resistance to antimicrobial peptides and various antibiotics, with vraDE specifically linked to bacitracin resistance.

Gene Information

Gene Name: vrade
Allele: vraDE
Encodes: ABC transporter
Source Database: Reslit
Mechanism: resistance to bacitracin
Confers Resistance To: Bacitracin
Organisms Tested In: • Staphylococcus aureus
Validation Method: mutant analysis and MIC testing

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