Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
two-component system
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| G223D | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| K208R | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| H364R | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| S221P | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| A96T | - | inhibiting the phosphorylation cascade and impairing cell wall modifications | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| A468T | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| A400V | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
Crosstalk involving two-component systems in Staphylococcus aureus signaling networks.
Review
Mutations in WalKR contribute to resistance against cell-wall-inhibiting antibiotics.
Antimicrobial Resistance: Two-Component Regulatory Systems and Multidrug Efflux Pumps.
Review
Impact of vancomycin use trend change due to the availability of alternative antibiotics on the prevalence of Staphylococcus aureus with reduced vancomycin susceptibility: a 14-year retrospective study.
Research Article