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Explore antimicrobial resistance genes from the literature

yTOP2

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to yTOP2

Browse AMR rules for yTOP2

Overview

Drug Classes: Ciprofloxacin
Organisms: Saccharomyces cerevisiae
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A484V	G1451T	-	Saccharomyces cerevisiae	Ciprofloxacin	Reslit	Candidate
G832S	G2495A	-	Saccharomyces cerevisiae	Ciprofloxacin	Reslit	Candidate

Papers1

1

A complex suite of loci and elements in eukaryotic type II topoisomerases determine selective sensitivity to distinct poisoning agents.

PMID 31287876 · 2019

Mutation Information

yTOP2: p.A484V yTOP2: p.G832S / c.G2495A

Protein Change: A484V, G832S
Nucleotide Change: G2495A
Organisms: Saccharomyces cerevisiae
Confers Resistance To: Ciprofloxacin
Source Database: Reslit