yeaN

Hypothetical membrane protein of Major Facilitator Superfamily (transporter)

Validation StatusCandidate

Overview

Mechanism: SNP leading to T321T change
Validation Method: Whole genome sequencing and MIC testing
Drug Classes: Triclosan, Benzalkonium chloride, Chlorhexidine, Triclosan|Benzalkonium chloride|Chlorhexidine
Organisms: Salmonella enterica serovar Typhimurium, Salmonella enterica
Geographic Location: Europe
Papers: 1
Databases: Reslit
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	C321G	-	Salmonella enterica	Triclosan\|Benzalkonium chloride\|Chlorhexidine	Reslit	Candidate

Papers1

Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.

PMID 27411385 · 2016

The study identifies multiple genetic mutations in Salmonella enterica Typhimurium that contribute to biocide and antibiotic resistance, including changes in genes such as fabI, ftsK, yeaN, mipA, asnA, aarF, tolA, motB, tdcA, garA, and bigA.

Gene Information

Gene Name: yeaN
Allele: yeaN
Encodes: Hypothetical membrane protein of Major Facilitator Superfamily (transporter)
Source Database: Reslit
Mechanism: SNP leading to T321T change
Confers Resistance To: TriclosanBenzalkonium chlorideChlorhexidine
Organisms Tested In: • Salmonella enterica serovar Typhimurium
Geographic Location: Europe
Validation Method: Whole genome sequencing and MIC testing
Sequence Accession: FQ312003

Browse AMR Genes

yeaN

Mutations

Gene Information