Unknown
S80I
Gene: parC
Curation StatusNot Validated
Overview
- Resistance To
- Nalidixic acid,Ciprofloxacin
- Organisms
- Escherichia coli
- Paper
- 1
Paper Information1
1
Topoisomerase IV is a target of quinolones in Escherichia coli.
PMID 8524852 · 1995Unknown phenotype if each mutation occurs alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Mutation Information
- Gene Name
- parC
- Protein Change
- S80I
Effect on Function
Target modification
Confers Resistance To
Nalidixic acid,Ciprofloxacin
Organisms Observed In
• Escherichia coli
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