ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneampC

beta-lactamase

Protein ChangeS90A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: The nonphosphorylatable mutant S90A was found to be more resistant to imipenem
Resistance To: Imipenem
Organisms: Acinetobacter baumannii
Papers: 1

Paper Information1

Comparative Phosphoproteomics Reveals the Role of AmpC β-lactamase Phosphorylation in the Clinical Imipenem-resistant Strain Acinetobacter baumannii SK17.

PMID 26499836 · 2016

Phosphorylation of Ser-90 regulates β-lactamase activity and imipenem resistance.

Mutation Information

ampC: p.S90A

Protein Change: S90A
Organisms: Acinetobacter baumannii
Confers Resistance To

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Mutation Information