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Browse Mutations nfxBAT115CG

GenenfxB

transcriptional repressor of MexCD-OprJ efflux pump

Nucleotide ChangeAT115CG

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss-of-function
Resistance To: Ciprofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

nfxB as a novel target for analysis of mutation spectra in Pseudomonas aeruginosa.

PMID 23762483 · 2013

Inactivating mutations in nfxB lead to resistance to ciprofloxacin

Mutation Information

nfxB: c.AT115CG

Nucleotide Change: AT115CG
Organisms: Pseudomonas aeruginosa
Confers Resistance To: Ciprofloxacin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

loss-of-function

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research