ResLit - Antimicrobial Resistance Gene & Mutation Database

Generrs

ribosomal RNA small subunit

Nucleotide ChangeG1064A

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: 16S ribosomal RNA, Target modification
Resistance To: SPECTINOMYCIN, Spectinomycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

16S

Mutation Information

rrs: c.G1064A

Nucleotide Change: G1064A
Organisms: Escherichia coli
Confers Resistance To: SPECTINOMYCIN

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Mutation Information