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blaOXY-2

NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
AMR Rules
Browse AMR rules for blaOXY-2
Validation StatusCandidate

Overview

Papers
1
Mutations
2

Mutations

Protein ChangeNucleotide ChangeMechanismOrganismResistance ToDatabaseValidation Status
G20S-enhanced hydrolytic activity against monobactamsKlebsiella oxytoca-
Reslit
Candidate
D197N-enhanced hydrolytic activity against monobactamsKlebsiella oxytoca-
Reslit
Candidate
Papers1
1

The extended-spectrum K1 beta-lactamase from Klebsiella oxytoca SC 10,436 is a member of the bla(OXY-2) family of chromosomal Klebsiella enzymes.

PMID 12019142 · 2002

The promoter region mutations enhance hydrolytic activity against monobactams.

Mutation Information

blaOXY-2: p.G20SblaOXY-2: p.D197N
Protein Change
G20S, D197N
Organisms
Klebsiella oxytoca
Effect on Function
enhanced hydrolytic activity against monobactams
Source Database
Reslit