ResLit

rrs

NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
Curation StatusNot Validated

Overview

Drug Classes
Amikacin, kanamycin, Amikacin,Capreomycin,KANAMYCIN, Amikacin,Capreomycin,KANAMYCIN,Streptomycin, amikacin|kanamycin|capreomycin, Gentamicin C, Kanamycin A, Neomycin, Paromomycin, Kasugamycin, Streptomycin, Spectinomycin, Amikacin,Streptomycin, Tetracycline, Doxycycline, Minocycline, Tigecycline, G418, Gentamicin C, Kanamycin A, Tobramycin
Organisms
Mycobacterium tuberculosis, Escherichia coli
Papers
20
Mutations
95
Mutations95
Nucleotide ChangeProtein ChangeTypeEffect on FunctionResistance ToYearPaperStatus
A1338C---
Amikacin
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
A1400G---
kanamycin
2009

Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa.

PMID: 19890396
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2013

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID: 23705640
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2013

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID: 23995137
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2013

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID: 23561273
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2012

Evaluation of genotype MTBDRsl assay to detect drug resistance associated with fluoroquinolones, aminoglycosides and ethambutol on clinical sediments.

PMID: 23166667
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2013

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID: 23561273
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2012

Detection of first- and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing.

PMID: 22461677
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2013

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID: 23705640
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2013

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID: 23288402
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2013

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID: 23995137
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2013

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID: 23906937
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2013

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID: 23288402
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2012

Detection of first- and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing.

PMID: 22461677
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2012

Evaluation of genotype MTBDRsl assay to detect drug resistance associated with fluoroquinolones, aminoglycosides and ethambutol on clinical sediments.

PMID: 23166667
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2013

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID: 23906937
Not Validated
A1401G---
Amikacin,Capreomycin,KANAMYCIN
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
A1401G---
amikacin|kanamycin|capreomycin
2010

Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.

PMID: 20713679
Not Validated
A1408G--Target modification
Gentamicin C, Kanamycin A, Neomycin, Paromomycin
2001

Aminoglycoside resistance with homogeneous and heterogeneous populations of antibiotic-resistant ribosomes.

PMID: 11502507
Not Validated
A1519C--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519C--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519C--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519G--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519G--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519G--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519T--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519T--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A1519T--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A514C---
Amikacin
2013

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID: 23561273
Not Validated
A514C---
Amikacin
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
A523C--Interference with drug-induced conformational modification
Streptomycin
1988

A mutation in the 530 loop of Escherichia coli 16S ribosomal RNA causes resistance to streptomycin.

PMID: 3054810
Not Validated
A794G--Target modification
Kasugamycin
1976

[The share of active nursing care in the overall nursing activities].

PMID: 1051271
Not Validated
A794G--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
A794T--Target modification
Kasugamycin
1976

[The share of active nursing care in the overall nursing activities].

PMID: 1051271
Not Validated
A794T--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
C1066T--Target modification
Spectinomycin
1995

A new mutation in 16S rRNA of Escherichia coli conferring spectinomycin resistance.

PMID: 7885842
Not Validated
C1192A--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192A--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192A--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192G--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192G--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192G--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192T--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192T--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1192T--Target modification
Spectinomycin
1984

Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli.

PMID: 6330677
Not Validated
C1192T--Target modification
Spectinomycin
1987

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID: 2447957
Not Validated
C1402A---
Amikacin,Capreomycin,KANAMYCIN
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
C1402A---
Amikacin,Capreomycin,KANAMYCIN
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
C1402A---
Amikacin,Capreomycin,KANAMYCIN
2013

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID: 23288402
Not Validated
C1402A---
Amikacin,Capreomycin,KANAMYCIN
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
C1402A---
Amikacin,Capreomycin,KANAMYCIN
2013

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID: 23705640
Not Validated
C1402A---
Amikacin,Capreomycin,KANAMYCIN
2013

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID: 23705640
Not Validated
C1402T---
Amikacin,Capreomycin,KANAMYCIN
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
C1402T---
Amikacin,Capreomycin,KANAMYCIN
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
C1402T---
Amikacin,Capreomycin,KANAMYCIN
2013

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID: 23705640
Not Validated
C1402T---
Amikacin,Capreomycin,KANAMYCIN
2013

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID: 23705640
Not Validated
C1402T---
Amikacin,Capreomycin,KANAMYCIN
2013

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID: 23288402
Not Validated
C1402T---
Amikacin,Capreomycin,KANAMYCIN
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
C517T---
Streptomycin
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
C517T---
Amikacin,Streptomycin
2013

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID: 23561273
Not Validated
C517T---
Amikacin,Streptomycin
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
C517T---
Streptomycin
2013

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID: 23561273
Not Validated
C517T---
Amikacin,Streptomycin
2013

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID: 23995137
Not Validated
C517T---
Streptomycin
2013

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID: 23995137
Not Validated
C517T---
Amikacin,Streptomycin
2013

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID: 23906937
Not Validated
C517T---
Streptomycin
2013

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID: 23906937
Not Validated
G1058C--Target modification
Tetracycline, Doxycycline, Minocycline, Tigecycline
2004

Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA.

PMID: 14985271
Not Validated
G1064A--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064A--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064A--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064C--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064C--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064C--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064T--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064T--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1064T--Target modification
Spectinomycin
1994

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID: 8127669
Not Validated
G1158T---
Amikacin
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
G1484T---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2013

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID: 23906937
Not Validated
G1484T---
amikacin|kanamycin|capreomycin
2010

Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.

PMID: 20713679
Not Validated
G1484T---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2012

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID: 22479378
Not Validated
G1484T---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2009

Tuberculosis drug resistance mutation database.

PMID: 19209951
Not Validated
G1484T---
Amikacin,Capreomycin,KANAMYCIN,Streptomycin
2012

Evaluation of genotype MTBDRsl assay to detect drug resistance associated with fluoroquinolones, aminoglycosides and ethambutol on clinical sediments.

PMID: 23166667
Not Validated
G926A--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926A--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926A--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926C--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926C--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926C--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926T--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926T--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
G926T--Target modification
Kasugamycin
1999

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID: 10512710
Not Validated
T1406A--Target modification
G418, Gentamicin C, Kanamycin A, Tobramycin
2001

Aminoglycoside resistance with homogeneous and heterogeneous populations of antibiotic-resistant ribosomes.

PMID: 11502507
Not Validated
Papers20
1

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A1338C

Confers Resistance To

Amikacin

Organisms Observed In

• Mycobacterium tuberculosis
2

Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa.

PMID 19890396 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
A1400G

Confers Resistance To

kanamycin

Organisms Observed In

• Mycobacterium tuberculosis
3

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
4

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID 23705640 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
5

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID 23995137 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
6

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID 23561273 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
7

Evaluation of genotype MTBDRsl assay to detect drug resistance associated with fluoroquinolones, aminoglycosides and ethambutol on clinical sediments.

PMID 23166667 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
8

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID 23561273 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
9

Detection of first- and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing.

PMID 22461677 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
10

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID 23705640 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
11

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
12

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID 23288402 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
13

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID 23995137 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
14

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
15

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID 23906937 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
16

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID 23288402 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
17

Detection of first- and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing.

PMID 22461677 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
18

Evaluation of genotype MTBDRsl assay to detect drug resistance associated with fluoroquinolones, aminoglycosides and ethambutol on clinical sediments.

PMID 23166667 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
19

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID 23906937 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
20

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
21

Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.

PMID 20713679 · 2010

Previously reported

Mutation Information

Gene Name
rrs
Nucleotide Change
A1401G

Confers Resistance To

amikacin|kanamycin|capreomycin

Organisms Observed In

• Mycobacterium tuberculosis
22

Aminoglycoside resistance with homogeneous and heterogeneous populations of antibiotic-resistant ribosomes.

PMID 11502507 · 2001

Mutation Information

Gene Name
rrs
Nucleotide Change
A1408G

Effect on Function

Target modification

Confers Resistance To

Gentamicin C, Kanamycin A, Neomycin, Paromomycin

Organisms Observed In

• Escherichia coli
23

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519C

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
24

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519C

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
25

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519C

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
26

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519G

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
27

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519G

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
28

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519G

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
29

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
30

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
31

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A1519T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
32

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID 23561273 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
A514C

Confers Resistance To

Amikacin

Organisms Observed In

• Mycobacterium tuberculosis
33

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
A514C

Confers Resistance To

Amikacin

Organisms Observed In

• Mycobacterium tuberculosis
34

A mutation in the 530 loop of Escherichia coli 16S ribosomal RNA causes resistance to streptomycin.

PMID 3054810 · 1988

Mutation Information

Gene Name
rrs
Nucleotide Change
A523C

Effect on Function

Interference with drug-induced conformational modification

Confers Resistance To

Streptomycin

Organisms Observed In

• Escherichia coli
35

[The share of active nursing care in the overall nursing activities].

PMID 1051271 · 1976

Mutation Information

Gene Name
rrs
Nucleotide Change
A794G

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
36

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A794G

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
37

[The share of active nursing care in the overall nursing activities].

PMID 1051271 · 1976

Mutation Information

Gene Name
rrs
Nucleotide Change
A794T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
38

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
A794T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
39

A new mutation in 16S rRNA of Escherichia coli conferring spectinomycin resistance.

PMID 7885842 · 1995

Mutation Information

Gene Name
rrs
Nucleotide Change
C1066T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
40

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192A

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
41

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192A

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
42

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192A

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
43

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192G

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
44

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192G

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
45

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192G

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
46

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
47

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
48

Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli.

PMID 6330677 · 1984

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
49

Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.

PMID 2447957 · 1987

Mutation Information

Gene Name
rrs
Nucleotide Change
C1192T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
50

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402A

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
51

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402A

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
52

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID 23288402 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402A

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
53

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402A

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
54

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID 23705640 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402A

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
55

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID 23705640 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402A

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
56

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
57

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
58

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID 23705640 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
59

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.

PMID 23705640 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
60

Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

PMID 23288402 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
61

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
C1402T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN

Organisms Observed In

• Mycobacterium tuberculosis
62

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
63

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID 23561273 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Amikacin,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
64

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Amikacin,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
65

Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.

PMID 23561273 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
66

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID 23995137 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Amikacin,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
67

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.

PMID 23995137 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
68

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID 23906937 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Amikacin,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
69

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID 23906937 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
C517T

Confers Resistance To

Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
70

Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA.

PMID 14985271 · 2004

Tigecycline borderline resistance

Mutation Information

Gene Name
rrs
Nucleotide Change
G1058C

Effect on Function

Target modification

Confers Resistance To

Tetracycline, Doxycycline, Minocycline, Tigecycline

Organisms Observed In

• Escherichia coli
71

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064A

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
72

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064A

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
73

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064A

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
74

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064C

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
75

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064C

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
76

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064C

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
77

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
78

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
79

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Mutation Information

Gene Name
rrs
Nucleotide Change
G1064T

Effect on Function

Target modification

Confers Resistance To

Spectinomycin

Organisms Observed In

• Escherichia coli
80

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
G1158T

Confers Resistance To

Amikacin

Organisms Observed In

• Mycobacterium tuberculosis
81

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.

PMID 23906937 · 2013

Mutation Information

Gene Name
rrs
Nucleotide Change
G1484T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
82

Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.

PMID 20713679 · 2010

Previously reported

Mutation Information

Gene Name
rrs
Nucleotide Change
G1484T

Confers Resistance To

amikacin|kanamycin|capreomycin

Organisms Observed In

• Mycobacterium tuberculosis
83

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PMID 22479378 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
G1484T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
84

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Gene Name
rrs
Nucleotide Change
G1484T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
85

Evaluation of genotype MTBDRsl assay to detect drug resistance associated with fluoroquinolones, aminoglycosides and ethambutol on clinical sediments.

PMID 23166667 · 2012

Mutation Information

Gene Name
rrs
Nucleotide Change
G1484T

Confers Resistance To

Amikacin,Capreomycin,KANAMYCIN,Streptomycin

Organisms Observed In

• Mycobacterium tuberculosis
86

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926A

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
87

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926A

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
88

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926A

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
89

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926C

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
90

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926C

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
91

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926C

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
92

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
93

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
94

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

PMID 10512710 · 1999

Mutation Information

Gene Name
rrs
Nucleotide Change
G926T

Effect on Function

Target modification

Confers Resistance To

Kasugamycin

Organisms Observed In

• Escherichia coli
95

Aminoglycoside resistance with homogeneous and heterogeneous populations of antibiotic-resistant ribosomes.

PMID 11502507 · 2001

Mutation Information

Gene Name
rrs
Nucleotide Change
T1406A

Effect on Function

Target modification

Confers Resistance To

G418, Gentamicin C, Kanamycin A, Tobramycin

Organisms Observed In

• Escherichia coli