-11 Mutation in the ampC promoter increasing resistance to beta-lactams in a clinical Escherichia coli strain.

PMID: 122348562002

Key Findings

A -11 C-to-T transition in the ampC promoter of a clinical E. coli strain increased beta-lactam resistance by enhancing promoter strength and AmpC beta-lactamase production.

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1gene entry

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
ampC	1	beta-lactamase	-	Escherichia coli	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampC	-	C-11T	increasing resistance	Escherichia coli	-	Reslit	-

Browse Papers

-11 Mutation in the ampC promoter increasing resistance to beta-lactams in a clinical Escherichia coli strain.

AMR Genes

AMR Mutations