AAC(6′)-Iaf, a novel aminoglycoside 6′-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.

PMID: 193495162009Japan

Key Findings

The study identifies a novel aminoglycoside resistance gene, aac(6′)-Iaf, in multidrug-resistant Pseudomonas aeruginosa clinical isolates. This gene encodes a functional aminoglycoside 6′-N-acetyltransferase that confers resistance to amikacin, dibekacin, and kanamycin.

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4gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
aac(6')	2	aminoglycoside 6'-N-acetyltransferase	AmikacinKanamycinAMINOGLYCOSIDETOBRAMYCINAMIKACINSISOMICINDIBEKACINNETILMICIN	Pseudomonas aeruginosa Escherichia coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Browse Papers

AAC(6′)-Iaf, a novel aminoglycoside 6′-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.

AMR Genes