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AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening.

PMID: 201324452010

Key Findings

Suppressor mutation in acrA that increases vancomycin sensitivity in the context of TolC 147AGSG150

0gene entries

1mutation entry

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
acrA	S83G	A248G	-	Escherichia coli	Vancomycin	Reslit	-