A two-component regulatory system interconnects resistance to polymyxins, aminoglycosides, fluoroquinolones, and β-lactams in Pseudomonas aeruginosa.

PMID: 211496192011

Key Findings

parR

0gene entries

4mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parR	M59I	G177A	two-component response regulator ParR	Pseudomonas aeruginosa	COLISTINColistin\|Imipenem	Reference Gene CatalogReslit	-
parS	L14Q	T41A	sensor histidine kinase ParS	Pseudomonas aeruginosa	CARBAPENEMColistin\|Imipenem	Reference Gene CatalogReslit	-